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Androsta-1,4,6-triene-3,17-dione
Catalog No. T10321Cas No. 633-35-2
Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor (Ki: 0.18 μM) that inhibits estrogen biosynthesis, exhibits antifertility effects, and induces impairment of spatial memory.
Androsta-1,4,6-triene-3,17-dione
Catalog No. T10321Cas No. 633-35-2
Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor (Ki: 0.18 μM) that inhibits estrogen biosynthesis, exhibits antifertility effects, and induces impairment of spatial memory.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor (Ki: 0.18 μM) that inhibits estrogen biosynthesis, exhibits antifertility effects, and induces impairment of spatial memory. |
| Targets&IC50 | Aromatase:ki:0.18 μM |
| In vivo | Androsta-1,4,6-triene-3,17-dione may inhibit fertility in vivo by suppressing estrogen biosynthesis [1]. Administered subcutaneously at doses of 25-100 mg/kg, it prevents the normal increase in ovarian estradiol concentrations [2]. |
| Molecular Weight | 282.38 |
| Formula | C19H22O2 |
| Cas No. | 633-35-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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