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Vorozole
🥰Excellent
Catalog No. T26322Cas No. 129731-10-8
Alias R83842, R-83839, R83839, R 83839, (+)-Vorozole
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the study of breast cancer.
Vorozole
🥰Excellent
Purity: 100%
Catalog No. T26322Alias R83842, R-83839, R83839, R 83839, (+)-VorozoleCas No. 129731-10-8
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the study of breast cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $191 | In Stock | |
| 5 mg | $480 | In Stock | |
| 10 mg | $687 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,480 | In Stock |
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Purity:100%
ee:99.84%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the study of breast cancer. |
| In vitro | Vorozole inhibits aromatase activity in FSH-stimulated rat granulosa cells with an IC 50 s of 1.4 nM.[3] |
| In vivo | Vorozole (0.8-1.25 mg/kg; Gavage; daily for 77 days; Female Sprague-Dawley rats) demonstrates antitumor effects and increases serum levels of insulin-like growth factor (IGF)-1 and testosterone.[3] Additionally, Vorozole (0.8-1.25 mg/kg; p.o.; 5 days; Female Sprague-Dawley rats) reduces uterine weight in a dose-dependent manner and effectively suppresses tumor aromatase in ovariectomized nude mice.[3] |
| Alias | R83842, R-83839, R83839, R 83839, (+)-Vorozole |
| Molecular Weight | 324.77 |
| Formula | C16H13ClN6 |
| Cas No. | 129731-10-8 |
| Smiles | [C@@H](C=1C=C2C(=CC1)N=NN2C)(C3=CC=C(Cl)C=C3)N4C=NC=N4 |
| Relative Density. | 1.44g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (153.96 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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