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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $67 | In Stock | |
2 mg | $98 | In Stock | |
5 mg | $163 | In Stock | |
10 mg | $255 | In Stock | |
25 mg | $452 | In Stock | |
50 mg | $657 | In Stock | |
100 mg | $935 | In Stock | |
1 mL x 10 mM (in DMSO) | $178 | In Stock |
Description | GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays). |
In vitro | GSK2795039 (25 μM; 24 hours) mitigates FeSO4 and LPS-induced apoptosis and reduces caspase-3-positive PC12 cells[2]. |
In vivo | GSK2795039 (intraperitoneal injection; 100 mg/kg; 1 hour prior) reduces activity in a murine acute pancreatitis model and decreases serum amylase levels induced by systemic cerulein injection[1]. |
Molecular Weight | 450.56 |
Formula | C23H26N6O2S |
Cas No. | 1415925-18-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (88.78 mM), Sonication is recommended. ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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