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Molibresib besylate (GSK 525762C) is a selective and potent inhibitor of the bromodomain and extra-terminal (BET) family of proteins with potential anticancer activity for the study of refractory hematologic malignant diseases.Molibresib besylate generates reactive oxygen species (ROS), which potentiate ATM activation.
Pack Size | Price | Availability | Quantity |
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2 mg | $149 | In Stock |
Description | Molibresib besylate (GSK 525762C) is a selective and potent inhibitor of the bromodomain and extra-terminal (BET) family of proteins with potential anticancer activity for the study of refractory hematologic malignant diseases.Molibresib besylate generates reactive oxygen species (ROS), which potentiate ATM activation. |
Targets&IC50 | BET:32.5-42.5 nM |
Alias | I-BET 762 besylate, GSK 525762C |
Molecular Weight | 582.07 |
Formula | C28H28ClN5O5S |
Cas No. | 1895049-20-3 |
Smiles | S(=O)(=O)(O)C1=CC=CC=C1.O(C)C=1C=C2C(N3C([C@H](CC(NCC)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)=CC1 |
Relative Density. | no data available |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (34.36 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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