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Elsinochrome A
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Catalog No. T35549Cas No. 24568-67-0
Elsinochrome A is a natural perylenequinone photosensitizer with antifungal activity, inducing apoptosis and autophagy through reactive oxygen species (ROS) generation upon photoactivation, involved in photodynamic therapy (PDT).
Elsinochrome A
😃Good
Catalog No. T35549Cas No. 24568-67-0
Elsinochrome A is a natural perylenequinone photosensitizer with antifungal activity, inducing apoptosis and autophagy through reactive oxygen species (ROS) generation upon photoactivation, involved in photodynamic therapy (PDT).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $869 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Elsinochrome A is a natural perylenequinone photosensitizer with antifungal activity, inducing apoptosis and autophagy through reactive oxygen species (ROS) generation upon photoactivation, involved in photodynamic therapy (PDT). |
| In vitro | The MIC value of Elsinochrome A against Candida albicans was 1 μg/mL. Elsinochrome A (2, 4, 8, 16 and 32 μg/mL) treated the suspension of Candida albicans (106 CFU/mL). The results showed that the SMIC80 of Elsinochrome A against Candida albicans biofilm was 16 μg/mL. The results indicated that Elsinochrome A had strong anti-candida albicans activity. [1] When Hce-8693 cells were incubated with photoactivated Elsinochrome A, apoptosis was induced in a dose-dependent manner. [2] |
| Molecular Weight | 544.51 |
| Formula | C30H24O10 |
| Cas No. | 24568-67-0 |
| Smiles | C(C)(=O)[C@H]1C=2C=3C4=C5C(=C6C3C(C(=O)C2OC)=C(O)C=C6OC)C(OC)=CC(O)=C5C(=O)C(OC)=C4[C@@H]1C(C)=O |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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