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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $183 | 35 days | |
5 mg | $793 | 35 days | |
10 mg | $1,430 | 35 days |
Description | Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
Alias | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide |
Molecular Weight | 441.612 |
Formula | C27H39NO4 |
Cas No. | 1138395-10-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMF: 25 mg/mL PBS (pH 7.2): 0.25 mg/mL Ethanol: 50 mg/mL DMSO: 25 mg/mL Acetonitrile: 3 mg/mL |
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