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17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
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17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

Catalog No. T37941Cas No. 1138395-10-4
Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
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Pack SizePriceAvailabilityQuantity
1 mg$18335 days
5 mg$79335 days
10 mg$1,43035 days
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Product Introduction

Bioactivity
Description
Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Alias17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
Chemical Properties
Molecular Weight441.612
FormulaC27H39NO4
Cas No.1138395-10-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMF: 25 mg/mL
PBS (pH 7.2): 0.25 mg/mL
Ethanol: 50 mg/mL
DMSO: 25 mg/mL
Acetonitrile: 3 mg/mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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