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Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting breast cancer growth and metastasis, enhancing mitochondrial function in synaptosomes, and inhibiting tumor-induced angiogenesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $118 | In Stock | |
10 mg | $178 | In Stock | |
25 mg | $409 | In Stock | |
50 mg | $698 | In Stock |
Description | Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting breast cancer growth and metastasis, enhancing mitochondrial function in synaptosomes, and inhibiting tumor-induced angiogenesis. |
Targets&IC50 | HCT116 cells:45.84 μM, LoVo cells:28.11 μM |
In vitro | After treating HCT116 and LoVo cells with different concentrations of Decylubiquinone for 96 h, Decylubiquinone significantly reduced the proliferation of HCT116 and LoVo cells in a dose-dependent manner. The IC50 values were 45.84 μM and 28.11 μM, respectively. [1] Decylubiquinone (50 μm) significantly increased the activity of the ETC complex in the synaptosome. [2] |
In vivo | In mouse CRC CT26 cell xenotransplantation model, Decylubiquinone (5 mg/kg, 12 days) was intraperitoneally injected, and it was found that Decylubiquinone significantly reduced CRC growth. [1] |
Alias | 6-Decylubiquinone |
Molecular Weight | 322.44 |
Formula | C19H30O4 |
Cas No. | 55486-00-5 |
Smiles | O=C1C(OC)=C(OC)C(=O)C(=C1C)CCCCCCCCCC |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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