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Isodeoxyelephantopin
🥰Excellent
Catalog No. TN1141Cas No. 38927-54-7
Isodeoxyelephantopin can inhibit the growth of various tumor cells.
Isodeoxyelephantopin
🥰Excellent
Purity: 99.88%
Catalog No. TN1141Cas No. 38927-54-7
Isodeoxyelephantopin can inhibit the growth of various tumor cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $272 | In Stock | |
| 5 mg | $677 | In Stock | |
| 10 mg | $957 | In Stock | |
| 25 mg | $1,420 | In Stock | |
| 50 mg | $1,890 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $673 | In Stock |
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Purity:99.88%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kap |
| In vitro | Isodeoxyelephantopin inhibits the growth of A549 and T47D cells in a dose-dependent and time-dependent manner with IC50 values of 10.46 and 1.3 μg/mL, respectively. Heterodeoxyelephantin showed no significant toxicity to normal lymphocytes. Heterodeoxyelephinin-induced cell death is associated with activated caspase-3 expression, followed by cell cycle stagnation in G2/M phase [1] |
| Molecular Weight | 344.36 |
| Formula | C19H20O6 |
| Cas No. | 38927-54-7 |
| Smiles | [H][C@]12C\C(C)=C/[C@@]3([H])OC(=O)C(=C)[C@]3([H])[C@H](CC(=C1)C(=O)O2)OC(=O)C(C)=C |
| Relative Density. | 1.26 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (159.72 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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