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Prostaglandin F2α 1,11-lactone

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Catalog No. T37326Cas No. 62410-84-8
Alias Prostaglandin F2α 1,11-lactone, PGF2α 1,11-lactone

Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.

Prostaglandin F2α 1,11-lactone

Prostaglandin F2α 1,11-lactone

😃Good
Catalog No. T37326Alias Prostaglandin F2α 1,11-lactone, PGF2α 1,11-lactoneCas No. 62410-84-8
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.
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10 mg$1,70035 days
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Product Introduction

Bioactivity
Description
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.
AliasProstaglandin F2α 1,11-lactone, PGF2α 1,11-lactone
Chemical Properties
Molecular Weight336.47
FormulaC20H32O4
Cas No.62410-84-8
SmilesC(=C/[C@H](CCCCC)O)\[C@H]1[C@]2(C[C@H](O)[C@@]1(C/C=C\CCCC(=O)O2)[H])[H]
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH 7.2): <50 μg/mL
Ethanol:PBS (30:70): 8 mg/mL
DMSO: 9 mg/mL (26.7 mM)
Ethanol: >100 mg/mL
DMF: >20 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9720 mL14.8602 mL29.7203 mL148.6017 mL
5 mM0.5944 mL2.9720 mL5.9441 mL29.7203 mL
10 mM0.2972 mL1.4860 mL2.9720 mL14.8602 mL
20 mM0.1486 mL0.7430 mL1.4860 mL7.4301 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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