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Ethamsylate
🥰Excellent
Catalog No. T0002Cas No. 2624-44-4
Alias Etamsylate, Dicynene, Cyclonamine, Aglumin
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins.
Ethamsylate
🥰Excellent
Purity: 99.98%
Catalog No. T0002Alias Etamsylate, Dicynene, Cyclonamine, AgluminCas No. 2624-44-4
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 g | $81 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
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Purity:99.98%
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins. |
| In vitro | High concentrations of Ethamsylate were able to remove superoxide radicals. In the presence of Ethamsylate, arachidonic acid, thromboxane A2, collagen, and the calcium carrier A23187 promoted the induction of human platelet aggregation and the release of ATP.Ethamsylate inhibited the production of prostaglandins in the microsomes of pregnant women's uterine myometrium at an IC50 of 0.5 mM. Ethamsylate was highly effective in inhibiting hydroxyl radicals (OH.) at concentrations of 0.1-10 μM. |
| In vivo | High concentrations of Ethamsylate were able to remove superoxide radicals. In the presence of Ethamsylate, arachidonic acid, thromboxane A2, collagen, and the calcium carrier A23187 promoted the induction of human platelet aggregation and the release of ATP.Ethamsylate inhibited the production of prostaglandins in the microsomes of pregnant women's uterine myometrium at an IC50 of 0.5 mM. Ethamsylate was highly effective in inhibiting hydroxyl radicals (OH.) at concentrations of 0.1-10 μM. |
| Alias | Etamsylate, Dicynene, Cyclonamine, Aglumin |
| Molecular Weight | 263.31 |
| Formula | C10H17NO5S |
| Cas No. | 2624-44-4 |
| Smiles | Oc1cc(c(O)cc1)S(=O)(=O)O.C(NCC)C |
| Relative Density. | 1.3441 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (189.89 mM)  | |||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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