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Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $218 | 35 days | |
10 mg | $1,700 | 35 days |
Description | Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
Alias | 17-phenoxy trinor Prostaglandin F2α ethyl amide |
Molecular Weight | 431.573 |
Formula | C25H37NO5 |
Cas No. | 1421369-12-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMF: 50 mg/mL (115.86 mM), Sonication is recommended. PBS (pH 7.2): 0.5 mg/mL (1.16 mM), Sonication is recommended. DMSO: 50 mg/mL (115.86 mM), Sonication is recommended. Ethanol: 50 mg/mL (115.86 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMF/DMSO/Ethanol
DMF/DMSO/Ethanol
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