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17-phenoxy trinor Prostaglandin F2α ethyl amide

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Catalog No. T37938Cas No. 1421369-12-1
Alias 17-phenoxy trinor Prostaglandin F2α ethyl amide

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

17-phenoxy trinor Prostaglandin F2α ethyl amide

17-phenoxy trinor Prostaglandin F2α ethyl amide

😃Good
Catalog No. T37938Alias 17-phenoxy trinor Prostaglandin F2α ethyl amideCas No. 1421369-12-1
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
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10 mgInquiry35 days
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Product Introduction

Bioactivity
Description
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Alias17-phenoxy trinor Prostaglandin F2α ethyl amide
Chemical Properties
Molecular Weight431.573
FormulaC25H37NO5
Cas No.1421369-12-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 50 mg/mL (115.86 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (1.16 mM), Sonication is recommended.
DMSO: 50 mg/mL (115.86 mM), Sonication is recommended.
Ethanol: 50 mg/mL (115.86 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.3171 mL11.5855 mL23.1711 mL115.8553 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
5 mM0.4634 mL2.3171 mL4.6342 mL23.1711 mL
10 mM0.2317 mL1.1586 mL2.3171 mL11.5855 mL
20 mM0.1159 mL0.5793 mL1.1586 mL5.7928 mL
50 mM0.0463 mL0.2317 mL0.4634 mL2.3171 mL
100 mM0.0232 mL0.1159 mL0.2317 mL1.1586 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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