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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $550 | Backorder | |
1 mL x 10 mM (in DMSO) | $850 | Backorder |
Description | Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet. |
In vitro | METHODS AND RESULTS:Three kinds of new coumarin-glycosides, Decuroside I (1), Decuroside II (2), Decuroside III (3), which were isolated from the N-butanol extracts of the crude drug Zi-Hua Qian-Hu, the root of PEUCEDANUM DECURSIVUM Maxim. (Umbelliferae), were elucidated to be nodakenetin-4′- O-β-gentiobiose, nodakenetin-4′- Oβ-isomaltose and nodakenetin-4′- O-β-maltose, respectively, by the methods of chemical and spectral analysis. These three new compounds as well as Decuroside IV (4), decuroside V (5) and nodakenin (6) which were also isolated from Zi-Hua Qian-Hu were tested on human platelet aggregation induced by 2 μM ADP. CONCLUSIONS:Among these coumarin-glycosides, 3 and 4, showed the strongest inhibiting activity against the primary and secondary wave aggregation of human platelet. 1 and 2 had a less inhibiting effect or none at all, and 5 was rather promotive against the primary wave aggregation. |
Molecular Weight | 570.544 |
Formula | C26H34O14 |
Cas No. | 96638-79-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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