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LDHA-IN-8, a small molecule inhibitor of lactate dehydrogenase A (LDHA), inhibits the proliferation of pancreatic and lung cancer cells by inhibiting the activity of LDHA-catalyzed pyruvate in a dose-dependent manner (EC 50=14.54μM), decreasing the intracellular lactate content and increasing the intracellular reactive oxygen species (ROS) levels.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $98 | In Stock | |
5 mg | $227 | In Stock | |
10 mg | $340 | In Stock | |
25 mg | $570 | In Stock | |
50 mg | $854 | In Stock | |
100 mg | $1,280 | In Stock | |
500 mg | $2,818 | In Stock |
Description | LDHA-IN-8, a small molecule inhibitor of lactate dehydrogenase A (LDHA), inhibits the proliferation of pancreatic and lung cancer cells by inhibiting the activity of LDHA-catalyzed pyruvate in a dose-dependent manner (EC 50=14.54μM), decreasing the intracellular lactate content and increasing the intracellular reactive oxygen species (ROS) levels. |
Molecular Weight | 282.3 |
Formula | C15H14N4O2 |
Cas No. | 347380-13-6 |
Smiles | O=C1NC(=O)C(=CC=2C=C(N(C=3C=NC=CC3)C2C)C)N1 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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