Liposome

5A2-SC8 is an ionizable cationic lipid that is an ideal vehicle for the delivery of small RNAs, interacts with negatively charged cell membranes, and can be used for gene delivery and drug delivery.

Vaxfectin is a lipid adjuvant used in the development of protein and peptide vaccines.Vaxfectin promotes vaccine immunogenicity.

DSPE-PEG 2000 is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

G0-C14 is a cationic lipid-like molecule commonly used for synthesizing nanoparticles and vaccine delivery.

NT1-O14B is a novel class of neurotransmitter tryptophan lipids (NT-lipidoids).NT1-O14B can be combined with small molecule drugs (e.g., AmB) and biomolecules (e.g., Tau-ASO) and gene editing proteins (GFP-Cre) to form new neurotransmitter-derived lipid nanoparticles (NT-LNPs) that have blood-brain-barrier (BBB) permeability. Enhanced lipid hydrophobicity and membrane fusion capabilities are commonly used for delivery of nucleic acids such as mRNA, siRNA and DNA.

POPG sodium salt is a phospholipid with a negative charge and is a component of biological membranes. It can be used to study the function of biological membranes.

C14-4 (C14-494) is an ionizable lipid nanoparticle used for delivering CAR mRNA to primary human T cells.

DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers.

4A3-SC8 is a modular dendritic macromolecule with cationic and lipophilic groups that enables small RNAs to prolong survival in an aggressive hepatocellular carcinoma model and can be used to synthesize lipid nanoparticles.

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium, catalog number T67435 and CAS number 200880-42-8, is a valuable organic compound for life sciences research.

(Rac)-DSPG sodium ((Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium) is a derivative of phosphatidylglycerol, which, as an amphiphilic molecule, is commonly used in the study of drug delivery and biofilm research.

DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.

Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.

NHLP-002 (BP Lipid 218) is an ionizable liposome that can be used to make nanoparticles, often in the form of nanoparticles to deliver mRNA drugs.

Dihexadecyl hydrogen phosphate is a phospholipid analog that acts as an emulsifier and is commonly used in the skin care and pharmaceutical industries.

CP-LC-1143 is an ionizable cationic amino lipid employed for the delivery of various RNA forms, including mRNA, cRNA, and saRNA.

DSPE-PEG(2000)-amine is a polyethylene glycol derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine, utilized in synthesizing solid lipid and thermosensitive liposome nanoparticles for cancer drug delivery.

Cardiolipin (16:1 16:1 16:1 16:1) (sodium salt) is an anionic phospholipid that enhances hydroxyapatite crystallization and supersaturation in calcium solution.

Lipid catechol is a lipid that forms lipid prodrug nanoassemblies (LPNA) with boronic acid-containing compounds. It holds potential for research in drug delivery.

Lipid C2 is an ionizable cationic lipid utilized in the formation of lipid nanoparticles (LNP) for the delivery of mRNA in vivo. LNPs containing Lipid C2 and encapsulating mRNA reporter genes specifically accumulate in the liver and spleen of mice, while avoiding the heart, lungs, and kidneys. Additionally, LNPs with Lipid C2 that encapsulate mRNA encoding Epstein-Barr virus (EBV) protein Latent Membrane Protein 2 (LMP-2), when combined with anti-programmed cell death protein 1 (PD-1) antibodies, have been shown to reduce tumor size, reverse T cell exhaustion, increase the percentage of CD3+CD8+ central T cells and CD3+CD8+ effector memory T cells in the spleen, and decrease the percentage of CD3+T cells expressing Pd-1 in a CT26 mouse model of EBV-infected colon cancer.

CP-LC-0743 is an ionizable cationic amino lipid that can be utilized to deliver various types of RNA, including mRNA, cRNA, and saRNA.

PEG(2000)-C-DMG is a polyethylene glycolated derivative of 1,2-Dimyristoyl-sn-glycerol and can be combined with other lipids to form lipid nanoparticles (LNP) for siRNA delivery.

IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.

Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.

C16 Ceramide (d16:1,C16:0) is a bioactive sphingolipid that induces the formation and thermal stabilization of ordered phases and gel phases enriched in palmitoyl sphingomyelin domains within palmitoyl phosphatidylcholine (POPC) bilayers. It is found in human erythrocyte sphingomyelin.

eGFP mRNA-LNP (500 ng uL) is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, and cell viability. eGFP circRNA includes the Enhanced Green Fluorescent Protein (eGFP), which expresses green fluorescent protein upon entering cells. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry.

SIL lipid is a synthetic ionizable lipid utilized in the formulation of lipid nanoparticles (LNPs) for siRNA delivery.