Powder: -20°C for 3 years | In solvent: -80°C for 1 year
A-770041 is a selective and orally active inhibitor targeting the Src-family kinase, Lck, which plays a crucial role in T-cell signaling. With an IC50 value of 147 nM at 1 mM ATP, A-770041 demonstrates high specificity by being 300-fold more selective towards Lck over Fyn, another member of the Src family kinase.
Description | A-770041 is a selective and orally active inhibitor targeting the Src-family kinase, Lck, which plays a crucial role in T-cell signaling. With an IC50 value of 147 nM at 1 mM ATP, A-770041 demonstrates high specificity by being 300-fold more selective towards Lck over Fyn, another member of the Src family kinase. |
Molecular Weight | 621.73 |
Formula | C34H39N9O3 |
CAS No. | 869748-10-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: ≥ 100 mg/mL (160.84 mM)
You can also refer to dose conversion for different animals. More
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A-770041 869748-10-7 Angiogenesis Tyrosine Kinase/Adaptors Src selective concanavalin A inhibit acute rejection IL-2 A770041 Inhibitor T cell A 770041 rat small-molecule inhibitor