Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Altenusin is a natural nonsteroidal fungal metabolite, as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 389.00 | |
5 mg | In stock | $ 970.00 | |
10 mg | In stock | $ 1,289.00 | |
25 mg | In stock | $ 1,619.00 | |
50 mg | In stock | $ 2,500.00 | |
100 mg | In stock | $ 5,200.00 | |
500 mg | In stock | Inquiry |
Description | Altenusin is a natural nonsteroidal fungal metabolite, as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 μM. |
Targets&IC50 | FXR:EC50 : 3.2 ± 0.2 μM |
In vitro | Treatment of primary mouse hepatocytes with altenusin inhibited oleic acid–induced steatosis in vitro [1]. |
In vivo | Administration of 2076A protected mice from high-fat diet (HFD)-induced obesity by reducing the body weight and fat mass by 22.9% and 50.0%, respectively. Administration of 2076A also decreased the blood glucose level from 178.3 ± 12.4 mg/dl to 116.2 ± 4.1 mg/dl and the serum insulin level from 1.4 ± 0.6 ng/dl to 0.4 ± 0.1 ng/dl[1]. |
Molecular Weight | 290.27 |
Formula | C15H14O6 |
CAS No. | 31186-12-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Altenusin 31186-12-6 Metabolism FXR inhibit Alutenusin Inhibitor inhibitor