Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 40.00 | |
10 mg | In stock | $ 57.00 | |
25 mg | In stock | $ 94.00 | |
50 mg | In stock | $ 138.00 | |
100 mg | In stock | $ 198.00 | |
500 mg | In stock | $ 512.00 |
Description | Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS. |
In vivo | Vipadenant (0.3-30 mg/kg) produces a dose-dependent reduction in catalepsy. Vipadenant (10 mg/kg) does not produce any statistically significant dyskinetic episodes in 6-OHDA-lesioned rats during a 19-day dosing regimen[1]. In the mouse and rat haloperidol-induced hypolocomotion models, vipadenant has a minimum effective dose of 0.1 and 1 mg/kg, respectively. Vipadenant (3 and 10 mg/kg, p.o.) is able to increase contralateral rotations in 6-OHDA lesioned rats[2]. |
Synonyms | TMC114 |
Molecular Weight | 547.66 |
Formula | C27H37N3O7S |
CAS No. | 206361-99-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 35 mg/mL (78.14 mM)
You can also refer to dose conversion for different animals. More
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Darunavir 206361-99-1 Microbiology/Virology Proteases/Proteasome HIV Protease TMC114 AID Minimal TMC-114 cytotoxicity UIC 94017 Human immunodeficiency virus UIC94017 Inhibitor inhibit HIV UIC-94017 TMC 114 inhibitor