Moroxydine hydrochloride is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines. It has antiviral activity and is hel...
Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism. |
Pirodavir (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor. |
Desacetyl-nitazoxanide is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse tra...
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1. |
Cephalotaxine is an antiviral and an antitumor agent. |
Merimepodib is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH). |
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. |
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of fru...
1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Eps...
1. Epigoitrin has anti-virus activity. 2. Epigoitrin has anti-oxidant activity. 3. Epigoitrin has anti-inflammation activity. |
1. Hypericin has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting mono...
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the gr...
Isomangiferin has an antiviral effect, may due to their capability of inhibiting virus replication within cells. It also has antioxidant and radical-scavenging ...
Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM). |
Antiviral, anti HIV. |
||IRAK inhibitor 1
IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM). |
||IRAK inhibitor 6
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM). |
Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits ...
(+)-Usniacin is a naturally occurring dibenzofuran derivative found in several lichen species. |
Esculin is a glucoside found in horse chestnuts. |
CA-4948 (previously AU-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model. |
1,5-Dicaffeoylquinic acid has neuroprotective, and antioxidant effects, it can inhibition of GSK3β as well as the modulation of Bcl-2/Bax. |
Brincidofovir (CMX001) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, ...
PF06650833 is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and P...
3-Methoxyflavone is a Flavonoids, with antiviral activity |
Tetrahydroepiberberine, an isoquinoline alkaloid, has antifungal and selective inhibition against the PI-3 virus activities. |
5-Fluorocytidine with antiviral activity |
Epirengynic acid has antiviral activity against RSV |
Betulone is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane. |
||Ganoderic acid F
Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities. |
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0....
Pocapavir is an investigational enterovirus (EV) capsid inhibitor. |
Edoxudine, an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) m...
Riamilovir is a broad-spectrum antiviral drug candidate. |
An antiviral agent. |