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A2ti-2
🥰Excellent
Catalog No. T36433Cas No. 482646-13-9
Alias A2ti-2
A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection.
A2ti-2
🥰Excellent
Purity: 98.31%
Catalog No. T36433Alias A2ti-2Cas No. 482646-13-9
A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $98 | In Stock | |
| 5 mg | $243 | In Stock | |
| 10 mg | $367 | In Stock | |
| 25 mg | $715 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,360 | In Stock | |
| 500 mg | $2,730 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $268 | In Stock |
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CitedSelect Batch
Purity:98.31%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection. |
| Targets&IC50 | A2t:230 μM (IC50) |
| In vitro | A2ti-2 (compound 7a) functions as a blocker of the protein-protein interaction between annexin A2 and S100A10.[1] A2ti-2 reduction HPV16 PsV infection with <50% achieved at 100 μM. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 μM.[2] |
| Alias | A2ti-2 |
| Molecular Weight | 354.43 |
| Formula | C18H18N4O2S |
| Cas No. | 482646-13-9 |
| Smiles | Cc1ccccc1OCc1nnc(SCC(N)=O)n1-c1ccccc1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (705.36 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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