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(-)-Epicatechin gallate

🥰Excellent
Catalog No. T2732Cas No. 1257-08-5
Alias Epicatechin gallate, ECG, (−)-Epicatechin 3-gallate, (-)-Epicatechin 3-O-gallate, (-)-Epicatechin 3-gallate

(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.

(-)-Epicatechin gallate

(-)-Epicatechin gallate

🥰Excellent
Purity: 99.72%
Catalog No. T2732Alias Epicatechin gallate, ECG, (−)-Epicatechin 3-gallate, (-)-Epicatechin 3-O-gallate, (-)-Epicatechin 3-gallateCas No. 1257-08-5
(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.
Pack SizePriceAvailabilityQuantity
20 mg$50In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.72%
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Product Introduction

Bioactivity
Description
(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.
Targets&IC50
COX-1:7.5 μM.
AliasEpicatechin gallate, ECG, (−)-Epicatechin 3-gallate, (-)-Epicatechin 3-O-gallate, (-)-Epicatechin 3-gallate
Chemical Properties
Molecular Weight442.37
FormulaC22H18O10
Cas No.1257-08-5
SmilesO(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C=C4
Relative Density.1.80 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (124.33 mM)
H2O: 2.5 mg/mL (5.65 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.2606 mL11.3028 mL22.6055 mL113.0276 mL
5 mM0.4521 mL2.2606 mL4.5211 mL22.6055 mL
DMSO
1mg5mg10mg50mg
10 mM0.2261 mL1.1303 mL2.2606 mL11.3028 mL
20 mM0.1130 mL0.5651 mL1.1303 mL5.6514 mL
50 mM0.0452 mL0.2261 mL0.4521 mL2.2606 mL
100 mM0.0226 mL0.1130 mL0.2261 mL1.1303 mL

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