Shopping Cart

Remove All

Your shopping cart is currently empty

PCL 016

Select Batch

Purity:99.83%

Resource Download

COA HPLC HNMR

PCL 016

Catalog No. T4850Cas No. 98-98-6

PCL 016 (2-Picolinic acid) is a topical antiviral agent, which inhibits adenovirus replication in rabbit.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability	Quantity
500 mg	$41	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "PCL 016"

Product Introduction

Bioactivity

Description	PCL 016 (2-Picolinic acid) is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
In vitro	Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations.
Alias	2-Picolinic acid

Chemical Properties

Molecular Weight	123.11
Formula	C6H5NO2
Cas No.	98-98-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (406.14 mM)

H2O: 50 mg/mL

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	8.1228 mL	40.6141 mL	81.2282 mL	406.1408 mL
5 mM	1.6246 mL	8.1228 mL	16.2456 mL	81.2282 mL
10 mM	0.8123 mL	4.0614 mL	8.1228 mL	40.6141 mL
20 mM	0.4061 mL	2.0307 mL	4.0614 mL	20.3070 mL
50 mM	0.1625 mL	0.8123 mL	1.6246 mL	8.1228 mL
100 mM	0.0812 mL	0.4061 mL	0.8123 mL	4.0614 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc