Carboxylic Acid Fragment Library With Solubility

Solubility is one of the fundamental physicochemical properties of drug candidates, and early assessment of solubility properties can better interpret in vitro results and provide valuable information for the design of new molecules. Compounds with low solubility often produce erroneous results during functional assays, thus increasing the risk of obtaining false hits or leads. Measuring solubility at an early stage of the drug discovery process can identify potentially ambiguous activity data, such as false negatives due to poor solubility. The high solubility and good theoretical membrane permeability of soluble carboxylic acid fragment molecules can better address the limiting factors in drug discovery. Features:

• (1) Soluble carboxylic acid fragment compounds: 1509.
• (2) Soluble fluorinated carboxylic acid fragment molecules: 122.
• (3) Soluble diverse carboxylic acid fragment molecules: 103.
• (4) Highly soluble carboxylic acid fragment molecules: 352.

• Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
• Shipped with blue ice