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Carboxylic Acid Fragment Library With Solubility

Catalog No. L7870
  Library Compound List   Excel SDF

To meet the high demand for novel and small carboxylic acid fragments for FBDD, we have carefully selected and created a library of 1807 soluble carboxylic acid fragments.

In overall, carboxylic acid fragment molecules have great potential for drug discovery of novel and difficult targets, such as protein-protein interactions, due to binding affinity to so-called “hot-spot” residues.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Pack Size
1 mg
5 mg
10 mg
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

Solubility is one of the fundamental physicochemical properties of drug candidates, and early assessment of solubility properties can better interpret in vitro results and provide valuable information for the design of new molecules. Compounds with low solubility often produce erroneous results during functional assays, thus increasing the risk of obtaining false hits or leads. Measuring solubility at an early stage of the drug discovery process can identify potentially ambiguous activity data, such as false negatives due to poor solubility. The high solubility and good theoretical membrane permeability of soluble carboxylic acid fragment molecules can better address the limiting factors in drug discovery. Features:

  • (1) Soluble carboxylic acid fragment compounds: 1509.
  • (2) Soluble fluorinated carboxylic acid fragment molecules: 122.
  • (3) Soluble diverse carboxylic acid fragment molecules: 103.
  • (4) Highly soluble carboxylic acid fragment molecules: 352.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L7870)

Library Composition

Endogenous Metabolite (21)
Antibacterial (4)
Drug Metabolite (2)
iGluR (2)
Tyrosinase (1)
Reactive Oxygen Species (1)
PPAR (1)
NMDAR (1)
Influenza Virus (1)
Histamine Receptor (1)
GRK (1)
5-HT Receptor (1)
AChR (1)
DPP-4 (1)
COX (1)
Autophagy (1)
ATP Citrate Lyase (1)
Antioxidant (1)
Anti-infection (1)
Amino Acids and Derivatives (1)
Acyltransferase (1)
Virus Protease (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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