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HBF-0259

HBF-0259
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Purity:99.88%
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HBF-0259

Catalog No. T27527Cas No. 957011-15-3
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
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Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
2 mg$46In Stock
5 mg$76In Stock
10 mg$133In Stock
25 mg$225In Stock
50 mg$331In Stock
100 mg$473In Stock
500 mg$954In Stock
1 mL x 10 mM (in DMSO)$85In Stock
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Product Introduction

Bioactivity
Description
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
AliasHBF 0259
Chemical Properties
Molecular Weight364.2
FormulaC16H12Cl2FN5
Cas No.957011-15-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 98 mg/mL (269.08 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7457 mL13.7287 mL27.4574 mL137.2872 mL
5 mM0.5491 mL2.7457 mL5.4915 mL27.4574 mL
10 mM0.2746 mL1.3729 mL2.7457 mL13.7287 mL
20 mM0.1373 mL0.6864 mL1.3729 mL6.8644 mL
50 mM0.0549 mL0.2746 mL0.5491 mL2.7457 mL
100 mM0.0275 mL0.1373 mL0.2746 mL1.3729 mL

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