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Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | Inquiry | In Stock | |
5 mg | $33 | In Stock | |
10 mg | $53 | In Stock | |
25 mg | $108 | In Stock | |
50 mg | $178 | In Stock | |
100 mg | $267 | In Stock | |
500 mg | $659 | In Stock |
Description | Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2]. |
In vitro | Arbidol exhibits potent antiviral activity against a wide range of viruses, including influenza viruses A, B, and C, respiratory syncytial virus, SARS-CoV, adenovirus, parainfluenza type 5, poliovirus 1, rhinovirus 14, coxsackievirus B5, hantaan virus, Chikungunya virus, HBV, and HCV.[1] |
In vivo | Arbidol (25 and 45 mg/ml; p.o.; 6–8 weeks old BALB/c mice) shows a survival benefit to mice suffering from influenza infection. Increased the survival rate, inhibited the decrease of body weight at 45 mg/mL, and inhibited the increase of mice lung index at 25 mg/mL and 45 mg/mL compared to the virus group.[3] |
Alias | Umifenovir |
Molecular Weight | 477.42 |
Formula | C22H25BrN2O3S |
Cas No. | 131707-25-0 |
Smiles | O=C(OCC)C=1C=2C(=CC(Br)=C(O)C2CN(C)C)N(C1CSC=3C=CC=CC3)C |
Relative Density. | 1.37 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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