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Arbidol

Catalog No. T7911Cas No. 131707-25-0
Alias Umifenovir

Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].

Arbidol

Arbidol

Purity: 99.57%
Catalog No. T7911Alias UmifenovirCas No. 131707-25-0
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].
Pack SizePriceAvailabilityQuantity
2 mgInquiryIn Stock
5 mg$33In Stock
10 mg$53In Stock
25 mg$108In Stock
50 mg$178In Stock
100 mg$267In Stock
500 mg$659In Stock
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Purity:99.57%
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Product Introduction

Bioactivity
Description
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].
In vitro
Arbidol exhibits potent antiviral activity against a wide range of viruses, including influenza viruses A, B, and C, respiratory syncytial virus, SARS-CoV, adenovirus, parainfluenza type 5, poliovirus 1, rhinovirus 14, coxsackievirus B5, hantaan virus, Chikungunya virus, HBV, and HCV.[1]
In vivo
Arbidol (25 and 45 mg/ml; p.o.; 6–8 weeks old BALB/c mice) shows a survival benefit to mice suffering from influenza infection. Increased the survival rate, inhibited the decrease of body weight at 45 mg/mL, and inhibited the increase of mice lung index at 25 mg/mL and 45 mg/mL compared to the virus group.[3]
AliasUmifenovir
Chemical Properties
Molecular Weight477.42
FormulaC22H25BrN2O3S
Cas No.131707-25-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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