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YM-53403

Catalog No. T29187Cas No. 851331-05-0

YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections.

YM-53403

YM-53403

Purity: 99%
Catalog No. T29187Cas No. 851331-05-0
YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections.
Pack SizePriceAvailabilityQuantity
1 mg$350In Stock
5 mg$828In Stock
10 mg$1,130In Stock
25 mg$1,590In Stock
50 mg$1,980In Stock
100 mg$2,500In Stock
500 mg$4,900In Stock
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Purity:99%
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Product Introduction

Bioactivity
Description
YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections.
In vitro
YM-53403 (0.2 μM) reduced plaque with EC50 was 0.20 ± 0.05 μM.[2]
YM-53403 (50 μM) inhibited the life cycle of RSV at around 8 h post-infection in time-dependent, suggesting an inhibitory effect on early transcription and/or replication of the RSV genome. YM-53403 is an attractive compound for the treatment of RSV infection because of its highly potent anti-RSV activity and the new mode of action.[2]
Chemical Properties
Molecular Weight583.7
FormulaC36H29N3O3S
Cas No.851331-05-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (102.79 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7132 mL8.5660 mL17.1321 mL85.6604 mL
5 mM0.3426 mL1.7132 mL3.4264 mL17.1321 mL
10 mM0.1713 mL0.8566 mL1.7132 mL8.5660 mL
20 mM0.0857 mL0.4283 mL0.8566 mL4.2830 mL
50 mM0.0343 mL0.1713 mL0.3426 mL1.7132 mL
100 mM0.0171 mL0.0857 mL0.1713 mL0.8566 mL

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