Shopping Cart
- Remove All
Your shopping cart is currently empty
(R)-JAK2/STAT3-IN-10a
🥰Excellent
Catalog No. T72754LCas No. 2485758-49-2
(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
(R)-JAK2/STAT3-IN-10a
🥰Excellent
Purity: 98.34%
Catalog No. T72754LCas No. 2485758-49-2
(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "(R)-JAK2/STAT3-IN-10a"
Oxytetracycline Hydrochloride
Oxytetracycline.HCl, Oxytetracycline, Sodium Salt, Oxytetracycline HCl, Dalinmycin, Dalimycin, Biosolvomycin
T214302058-46-0
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.
- $41
Size
QTY
Valganciclovir hydrochloride
Valganciclovir HCl, Valcyte, Valcyt
T1533175865-59-5
Valganciclovir hydrochloride (Valganciclovir HCl) is a hydrochloride salt form of valganciclovir, a prodrug form of ganciclovir, a nucleoside analog of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, and viral replication.
- $30
Size
QTY
BTA-188
T67792314062-80-1In house
BTA-188 is one of the most potent analogues of novel and orally active synthetic benzoxazole and benzothiazole derivatives with significant anti-rhinovirus activity.
- $118
Size
QTY
Rociclovir PM
2-[(2-aminopurin-9-yl)methoxy]propane-1,3-diol
T6780789419-23-8In house
Rociclovir PM (2-[(2-aminopurin-9-yl)methoxy]propane-1,3-diol) is a compound with antiviral activity
- $118
Size
QTY
3-Methoxyflavone
T79947245-02-5
3-Methoxyflavone is a Flavonoids, with antiviral activity
- $30
Size
QTY
3-Methoxycatechol
1,2-Dihydroxy-3-methoxybenzene
T77555934-00-9
3-Methoxycatechol is a lignin-derived renewable chemical that promotes carcinogenesis in the esophagus.1,2-Dihydroxy-3-methoxybenzen exhibits strong antiviral activity against encephalomyelitis virus (EMCV).
- $29
Size
QTY
YM-53403
T29187851331-05-0In house
YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections.
- $350
Size
QTY
Arbidol
Umifenovir
T7911131707-25-0
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].
- Inquiry Price
Size
QTY
2,2'-Anhydrouridine
O2,2'-Cyclouridine, 2,2'-Cyclouridine
T59813736-77-4
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.
- $34
Size
QTY
(+)-Usnic acid
D-Usnic Acid, (+)-Usniacin
T63547562-61-0
(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.
- $29
Size
QTY
Tirilazad mesylate
U-74006F mesylate, U74006F mesylate, U-74006 mesylate, U74006 mesylate, U 74006F mesylate, U 74006 mesylate
T28978110101-67-2In house
Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral and neuroprotective activities. It confines intracellular intramembranous foci, attenuates spinal cord injuries induced by trauma, stroke, and ischemia/reperfusion injuries, inhibits toxins in dogs, and is used in the study of neurological disorders.
- $579
Size
QTY
Vidarabine phosphate
T2004829984-33-6
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
- $30
Size
QTY
Select Batch
Purity:98.34%
ee:99.94%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM. |
| Molecular Weight | 682.57 |
| Formula | C34H35BrF3N5O2 |
| Cas No. | 2485758-49-2 |
| Smiles | C(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy (R)-JAK2/STAT3-IN-10a | purchase (R)-JAK2/STAT3-IN-10a | (R)-JAK2/STAT3-IN-10a cost | order (R)-JAK2/STAT3-IN-10a | (R)-JAK2/STAT3-IN-10a chemical structure | (R)-JAK2/STAT3-IN-10a formula | (R)-JAK2/STAT3-IN-10a molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.