Isomyosmine is an isomer of myosine that inhibits nitrate reductase, has potential antiviral activity, reduces oxidative stress, can promote plant health and increase productivity and yield. Isomyosmine inhibits the release of TNF-α and can be used to study inflammation and coronavirus infection related to oxidoreductase.

b>METHODS: The study was conducted in a double-blind manner: subjects in each dose group (Groups 1, 2, 3, and 4) were randomly assigned to receive either Isomyosmine dose (between 150 mg and 600 mg or placebo) or placebo in a 3:1 ratio (6 active drugs: 2 placebos).
RESULTS: Single daily doses of Isomyosmine of 150 mg, 300 mg, and 450 mg for 3 consecutive days and multiple daily doses of 600 mg for 6 consecutive days were safe and well tolerated in healthy subjects; within one dose group, TNF-α levels decreased in subjects treated with Isomyosmine but did not change in subjects treated with placebo; when given as a single dose, the increase in Isomyosmine exposure was dose-proportional over the dose range of 300 mg to 600 mg. Minimal accumulation of Isomyosmine was observed after 5 consecutive days of Isomyosmine 600 mg daily. [1]