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Peramivir

Catalog No. T21339Cas No. 330600-85-6
Alias RWJ270201, RWJ 270201, BCX1812, BCX 1812

Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.

Peramivir

Peramivir

Purity: 99.82%
Catalog No. T21339Alias RWJ270201, RWJ 270201, BCX1812, BCX 1812Cas No. 330600-85-6
Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$106In Stock
25 mg$198In Stock
50 mg$292In Stock
100 mg$433In Stock
500 mg$987In Stock
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Purity:99.82%
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Product Introduction

Bioactivity
Description
Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
Targets&IC50
NA:IC50: 0.9-4.3 nM
In vitro
Peramivir (2-10 μM, 6-12 h) inhibits LPS-induced cytokine release from hPBMCs[4].
Peramivir (0.3125-40 μM, 4 h) is non-toxic to macrophages[4].
In vivo
Peramivir (20-60 mg/kg, intraperitoneal injection, single dose) inhibits LPS-induced cytokine storm, attenuates acute lung injury, and prolongs survival in a mouse model of cytokine storm syndrome [4].
Peramivir (75 mg/kg, intramuscular injection once daily for 7 days) rescued BR/08 lethally attacked BALB scid mice in an immunosuppressed mouse model of influenza B virus infection [5].
AliasRWJ270201, RWJ 270201, BCX1812, BCX 1812
Chemical Properties
Molecular Weight328.41
FormulaC15H28N4O4
Cas No.330600-85-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble.)

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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