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Peramivir

Peramivir
Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
Catalog No. T21339Cas No. 330600-85-6
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Purity:99.82%
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Peramivir

Purity: 99.82%
Catalog No. T21339Alias RWJ270201, RWJ 270201, BCX1812, BCX 1812Cas No. 330600-85-6

Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$106In Stock
25 mg$198In Stock
50 mg$292In Stock
100 mg$433In Stock
500 mg$987In Stock
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Product Introduction

Bioactivity
Description
Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
Targets&IC50
NA:IC50: 0.9-4.3 nM
In vitro
Peramivir (2-10 μM, 6-12 h) inhibits LPS-induced cytokine release from hPBMCs[4].
Peramivir (0.3125-40 μM, 4 h) is non-toxic to macrophages[4].
In vivo
Peramivir (20-60 mg/kg, intraperitoneal injection, single dose) inhibits LPS-induced cytokine storm, attenuates acute lung injury, and prolongs survival in a mouse model of cytokine storm syndrome [4].
Peramivir (75 mg/kg, intramuscular injection once daily for 7 days) rescued BR/08 lethally attacked BALB scid mice in an immunosuppressed mouse model of influenza B virus infection [5].
AliasRWJ270201, RWJ 270201, BCX1812, BCX 1812
Chemical Properties
Molecular Weight328.41
FormulaC15H28N4O4
Cas No.330600-85-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble.)

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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