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Immunology/Inflammation

Aryl Hydrocarbon Receptor

Immunology/Inflammation related

NOD-like Receptor (NLR)

Prostaglandin Receptor

Reactive Oxygen Species

Thrombopoietin Receptor

TROP2

Trophoblast Cell-Surface Antigen 2 (TROP2), a cell surface glycoprotein encoded and expressed by Tacstd2 gene in chromosome 1P32 region, is closely related to tumor. TROP2 primarily promotes the growth, proliferation, and metastasis of tumor cells by regulating Ca2+ signaling pathway, the expression of cyclin proteins, and reducing the adhesive function of fibronectin.

Filter HomeSignaling PathwaysImmunology/InflammationTROP2

Datopotamab

T9901A-0072267989-53-5

Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan).

$255

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Sacituzumab govitecan

T778241491917-83-9

Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.

$455

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Sacituzumab MMAE

T9901A-217

Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.

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