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WIN 54954
🥰Excellent
Catalog No. T61652Cas No. 107355-45-3
WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.
WIN 54954
🥰Excellent
Purity: 98.58%
Catalog No. T61652Cas No. 107355-45-3
WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $52 | In Stock | |
| 2 mg | $74 | In Stock | |
| 5 mg | $123 | In Stock | |
| 10 mg | $198 | In Stock | |
| 25 mg | $372 | In Stock | |
| 50 mg | $619 | In Stock | |
| 100 mg | $1,090 | In Stock | |
| 500 mg | $2,230 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $135 | In Stock |
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Purity:98.58%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections. |
| In vitro | WIN 54954 reduced plaque formation by 50 of 52 serotypes of rhinovirus (MIC range: 0.007 to 2.2 μg/ml). A concentration of 0.28 μg/ml effectively inhibited 80% of the 52 serotypes (EC80). WIN 54954 also effectively inhibited 15 commonly isolated enteroviruses, with an EC80 of 0.06 μg/ml[1]. |
| In vivo | A single gastric dose of WIN 54954 at daily doses of 2 and 100 mg/kg protected 50% of mice from paralysis after infection with Coxsackie virus A-9 and ECHO virus-9, respectively (PD50)[1]. |
| Molecular Weight | 383.27 |
| Formula | C18H20Cl2N2O3 |
| Cas No. | 107355-45-3 |
| Smiles | Cc1cc(CCCCCOc2c(Cl)cc(cc2Cl)C2=NCCO2)on1 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (208.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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