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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $52 | In Stock | |
2 mg | $74 | In Stock | |
5 mg | $123 | In Stock | |
10 mg | $198 | In Stock | |
25 mg | $372 | In Stock | |
50 mg | $619 | In Stock | |
100 mg | $1,090 | In Stock | |
500 mg | $2,230 | In Stock | |
1 mL x 10 mM (in DMSO) | $135 | In Stock |
Description | WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections. |
In vitro | WIN 54954 reduced plaque formation by 50 of 52 serotypes of rhinovirus (MIC range: 0.007 to 2.2 μg/ml). A concentration of 0.28 μg/ml effectively inhibited 80% of the 52 serotypes (EC80). WIN 54954 also effectively inhibited 15 commonly isolated enteroviruses, with an EC80 of 0.06 μg/ml[1]. |
In vivo | A single gastric dose of WIN 54954 at daily doses of 2 and 100 mg/kg protected 50% of mice from paralysis after infection with Coxsackie virus A-9 and ECHO virus-9, respectively (PD50)[1]. |
Molecular Weight | 383.27 |
Formula | C18H20Cl2N2O3 |
Cas No. | 107355-45-3 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (208.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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