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SARS-CoV-2 nsp13-IN-1

🥰Excellent
Catalog No. T62413Cas No. 1005304-44-8

SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 μM, but not ssDNA-ATPase, and can be used to study COVID-19.

SARS-CoV-2 nsp13-IN-1

SARS-CoV-2 nsp13-IN-1

🥰Excellent
Purity: 99.44%
Catalog No. T62413Cas No. 1005304-44-8
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 μM, but not ssDNA-ATPase, and can be used to study COVID-19.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$89In Stock
10 mg$147In Stock
25 mg$247In Stock
50 mg$365In Stock
100 mg$542In Stock
500 mg$1,180In Stock
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Purity:99.44%
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Product Introduction

Bioactivity
Description
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 μM, but not ssDNA-ATPase, and can be used to study COVID-19.
Targets&IC50
ATPase:6±0.5 μM
Chemical Properties
Molecular Weight432.47
FormulaC27H20N4O2
Cas No.1005304-44-8
SmilesCC1=NC2=C(C=CC=N2)C(=O)N1C1=CC=C(NC(=O)C2=CC=C(C=C2)C2=CC=CC=C2)C=C1
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (69.37 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3123 mL11.5615 mL23.1230 mL115.6150 mL
5 mM0.4625 mL2.3123 mL4.6246 mL23.1230 mL
10 mM0.2312 mL1.1561 mL2.3123 mL11.5615 mL
20 mM0.1156 mL0.5781 mL1.1561 mL5.7807 mL
50 mM0.0462 mL0.2312 mL0.4625 mL2.3123 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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