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Seselin

🥰Excellent
Catalog No. TN5891Cas No. 523-59-1

Seselin is a natural product from Plumbago zeylanica. Seselin shows anti-inflammatory and antiviral activity.

Seselin

Seselin

🥰Excellent
Purity: 100%
Catalog No. TN5891Cas No. 523-59-1
Seselin is a natural product from Plumbago zeylanica. Seselin shows anti-inflammatory and antiviral activity.
Pack SizePriceAvailabilityQuantity
1 mg$122In Stock
2 mg$178In Stock
5 mg$297In Stock
10 mg$453In Stock
25 mg$733In Stock
50 mg$987In Stock
100 mg$1,360In Stock
1 mL x 10 mM (in DMSO)$261In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Seselin is a natural product from Plumbago zeylanica. Seselin shows anti-inflammatory and antiviral activity.
In vitro
Seselin (10uM) blocked signalling pathways that mediate the classical activation of macrophages in bone marrow‐derived macrophages.
In vivo
Seselin (3mg/kg, 10mg/kg, 30mg/kg, iv) ameliorated lung injury and decreased JAK2 phosphorylation level in lung tissue during mouse sepsis.
Chemical Properties
Molecular Weight228.24
FormulaC14H12O3
Cas No.523-59-1
SmilesCC1(C)Oc2ccc3ccc(=O)oc3c2C=C1
Relative Density.1.351 g/cm3 at 18℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (197.16 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3814 mL21.9068 mL43.8135 mL219.0676 mL
5 mM0.8763 mL4.3814 mL8.7627 mL43.8135 mL
10 mM0.4381 mL2.1907 mL4.3814 mL21.9068 mL
20 mM0.2191 mL1.0953 mL2.1907 mL10.9534 mL
50 mM0.0876 mL0.4381 mL0.8763 mL4.3814 mL
100 mM0.0438 mL0.2191 mL0.4381 mL2.1907 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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