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Brincidofovir

🥰Excellent
Catalog No. TQ0095Cas No. 444805-28-1
Alias HDP-CDV, CMX001

Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.

Brincidofovir

Brincidofovir

🥰Excellent
Purity: 99.62%
Catalog No. TQ0095Alias HDP-CDV, CMX001Cas No. 444805-28-1
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$115In Stock
10 mg$173In Stock
25 mg$348In Stock
50 mg$522In Stock
100 mg$669In Stock
200 mg$953In Stock
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Related Compound Libraries of "Brincidofovir"

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Purity:99.62%
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Product Introduction

Bioactivity
Description
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.
Targets&IC50
Anti-CMV (in PDA at 7 dpi):5.5 nM (EC50)
AliasHDP-CDV, CMX001
Chemical Properties
Molecular Weight561.69
FormulaC27H52N3O7P
Cas No.444805-28-1
SmilesC([C@H](OCP(OCCCOCCCCCCCCCCCCCCCC)(=O)O)CO)N1C(=O)N=C(N)C=C1
Relative Density.1.17 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
0.1 M NaOH: 20 mg/mL (35.60 mM), Sonication is recommended.
DMSO: 1 mg/mL (1.78 mM), when pH is adjusted to 6 with NaOH. Heating to 50℃ is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO/0.1 M NaOH
1mg5mg10mg50mg
1 mM1.7803 mL8.9017 mL17.8034 mL89.0171 mL
0.1 M NaOH
1mg5mg10mg50mg
5 mM0.3561 mL1.7803 mL3.5607 mL17.8034 mL
10 mM0.1780 mL0.8902 mL1.7803 mL8.9017 mL
20 mM0.0890 mL0.4451 mL0.8902 mL4.4509 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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