Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 218.00 | |
25 mg | In stock | $ 369.00 | |
50 mg | In stock | $ 543.00 | |
100 mg | In stock | $ 776.00 | |
500 mg | In stock | $ 1,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 218.00 |
Description | Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs. |
Source |
Molecular Weight | 286.32 |
Formula | C17H18O4 |
CAS No. | 119425-89-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 86.6 mg/mL (302.46 mM)
You can also refer to dose conversion for different animals. More
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Loureirin A 119425-89-7 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt PI3K PKB Protein kinase B Inhibitor inhibit inhibitor