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Luteolin-7-rutinoside

Catalog No. T11895 CAS 20633-84-5

Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.

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Luteolin-7-rutinoside Chemical Structure

Luteolin-7-rutinoside, CAS 20633-84-5

Pack Size	Availability	Price/USD
1 mg	35 days	$ 188.00
5 mg	35 days	$ 597.00
10 mg	35 days	$ 1,120.00
25 mg	35 days	$ 2,340.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.

In vitro

Luteolin-7-rutinoside demonstrates dose-dependent immunomodulatory effects in T cells and macrophages. At concentrations of 40 μg/mL, it induces T cell proliferation at a rate comparable to that seen with 20 μg/mL, indicating a potential plateau in efficacy with increased dosage. A lower dose of 10 μg/mL (referred to as lonicerin) significantly reduces T cell proliferation by approximately 47% relative to control groups treated with Luteolin-7-rutinoside (p<0.05), highlighting its suppressive capability. Additionally, Luteolin-7-rutinoside shifts the Th1-Th2 balance towards Th2-type responses and inhibits nitric oxide (NO) production from macrophages, further evidencing its immunological influence.

Molecular Weight	594.52
Formula	C27H30O15
CAS No.	20633-84-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9.

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Keywords

Luteolin-7-rutinoside 20633-84-5 Others Luteolin 7 rutinoside Luteolin7rutinoside inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.