Powder: -20°C for 3 years | In solvent: -80°C for 1 year
P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
5 mg | In stock | $ 128.00 | |
10 mg | In stock | $ 213.00 | |
25 mg | In stock | $ 428.00 | |
50 mg | In stock | $ 639.00 | |
100 mg | In stock | $ 890.00 | |
500 mg | In stock | $ 1,830.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 148.00 |
Description | P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells). |
In vitro | In K562/A02 MDR cells, P-gp inhibitor 1 (0.1, 1, 5 μM, 1 h) boosts the potency of other MDR-related cytotoxic agents with different structures, increases the accumulation of DOX, blocks Pgp-mediated Rh123 efflux, and suppresses P-gp ATPase activity[1]. |
Molecular Weight | 517.62 |
Formula | C32H31N5O2 |
CAS No. | 2050747-49-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (86.94 mM)
You can also refer to dose conversion for different animals. More
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P-gp inhibitor 1 2050747-49-2 Membrane transporter/Ion channel Neuroscience Others P-gp P-glycoprotein inhibit Pgp inhibitor 1 Pgp CD243 MDR1 Cluster of differentiation 243 Multidrug resistance protein 1 Inhibitor ABCB1 P gp inhibitor 1 inhibitor