Powder: -20°C for 3 years | In solvent: -80°C for 1 year
THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 39.00 |
Description | THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1]. |
In vitro | PROTAC K-Ras Degrader-1 is potent?K-Ras?degrader based?PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 391.5 |
Formula | C19H37NO7 |
CAS No. | 2378261-81-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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THP-PEG4-Pyrrolidine(N-Me)-CH2OH 2378261-81-3 Others THP-PEG-4-Pyrrolidine(N-Me)-CH2OH THP PEG4 Pyrrolidine(N Me) CH2OH THPPEG4Pyrrolidine(NMe)CH2OH inhibitor inhibit