Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 μg | 35 days | $ 88.00 | |
100 μg | 35 days | $ 145.00 | |
500 μg | 35 days | $ 450.00 | |
1 mg | 35 days | $ 793.00 |
Description | Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A. |
Targets&IC50 | Proteasome:4.8 μM |
In vivo | After injection in young and adult mice, Lactacystin (microinjection; 2 μg) causes a Parkinson's disease-like motor phenotype 5-7 days [2]. |
Molecular Weight | 376.43 |
Formula | C15H24N2O7S |
CAS No. | 133343-34-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Lactacystin 133343-34-7 Proteases/Proteasome Ubiquitination Proteasome inhibitor inhibit