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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
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Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
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Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are called proteases.Proteasomes are part of a major mechanism by which cells regulate the concentration of particular proteins and degrade misfolded proteins.
Cat. No. Product name CAS No. Purity Chemical Structure
T15678 KZR-504 1629052-78-3 98%
KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
T11924 M3258 2285330-15-4 98%
LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor of imm...
T10238 Aclacinomycin A hydrochloride 75443-99-1 98%
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (c...
T15702 Lactacystin 133343-34-7 98%
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacyst...
T12561 Proteasome-IN-1 374080-21-4 98%
Proteasome-IN-1 is an inhibitor of proteasome.
T16568 PR-924 1416709-79-9 98%
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple...
T36902 RA375 98%
RA375 is a inhibitor of RPN13 (26S proteasome regulatory subunit). RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater a...
T7369 Gemigliptin 911637-19-9 98%
Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)
T7814 Alloxan monohydrate 2244-11-3 98%
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
T3359 Aprotinin 9087-70-1 98%
Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, ...
T2470 MDL-28170 88191-84-8 98%
Calpain Inhibitor III is a Cysteine protease.
T7133 Anagliptin 739366-20-2 98%
Anagliptin is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
T6999 Teneligliptin hydrobromide 906093-29-6 98%
Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-...
T12079 ML604440 1140517-08-3 98%
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
T8350 TPCK 402-71-1 98%
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
T21617 MG-115 133407-86-0 98%
MG-115 is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit t...
T67852 Linagliptin Methyldimer 1418133-47-7 98%
Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
T16169 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 4272-74-6 98%
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib...
T7854 Bortezomib-pinanediol 205393-22-2 98%
Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.
T13858 RA190 1617495-03-0 98%
RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
KZR-504
T15678
KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
M3258
T11924
LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor of imm...
Aclacinomycin A hydrochloride
T10238
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (c...
Lactacystin
T15702
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacyst...
Proteasome-IN-1
T12561
Proteasome-IN-1 is an inhibitor of proteasome.
PR-924
T16568
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple...
RA375
T36902
RA375 is a inhibitor of RPN13 (26S proteasome regulatory subunit). RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater a...
Gemigliptin
T7369
Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)
Alloxan monohydrate
T7814
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
Aprotinin
T3359
Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, ...
MDL-28170
T2470
Calpain Inhibitor III is a Cysteine protease.
Anagliptin
T7133
Anagliptin is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
Teneligliptin hydrobromide
T6999
Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-...
ML604440
T12079
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
TPCK
T8350
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
MG-115
T21617
MG-115 is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit t...
Linagliptin Methyldimer
T67852
Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride
T16169
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib...
Bortezomib-pinanediol
T7854
Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.
RA190
T13858
RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
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