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Alloxan monohydrate

🥰Excellent
Catalog No. T7814Cas No. 2244-11-3

Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.

Alloxan monohydrate

Alloxan monohydrate

🥰Excellent
Purity: 99.42%
Catalog No. T7814Cas No. 2244-11-3
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
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1 g$29In Stock
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Purity:99.42%
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Product Introduction

Bioactivity
Description
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
In vitro
Alloxan caused the accumulation of ubiquitinated proteins in NRK cells through the inhibition of the proteolytic activities of the proteasome.?Alloxan directly acts on the chymotrypsin- and trypsin-like peptidase activities[1]
Chemical Properties
Molecular Weight160.09
FormulaC4H4N2O5
Cas No.2244-11-3
SmilesO.O=C1NC(=O)C(=O)C(=O)N1
Relative Density.1.681g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (374.79 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.2465 mL31.2324 mL62.4649 mL312.3243 mL
5 mM1.2493 mL6.2465 mL12.4930 mL62.4649 mL
10 mM0.6246 mL3.1232 mL6.2465 mL31.2324 mL
20 mM0.3123 mL1.5616 mL3.1232 mL15.6162 mL
50 mM0.1249 mL0.6246 mL1.2493 mL6.2465 mL
100 mM0.0625 mL0.3123 mL0.6246 mL3.1232 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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