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product7/Tenovin-6.html

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  • Inhibitors & Agonists
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(6Z)-7-Phenyl-7-(3-Pyridinyl)-6-Heptenoic Acid
T7754889667-39-0In house
(6Z)-7-Phenyl-7-(3-Pyridinyl)-6-Heptenoic Acid is a derivative of 7-Phenyl-7-(3-Pyridyl) -6-Heptenoic Acid that can be used in biological research.
  • $195
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7-Methyl-6-mercaptopurine
T263993324-79-6In house
7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) is an inhibitor of PRPP aminotransferase, inhibits IMP metabolism and prevents purine, DNA and RNA synthesis.
  • $46
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Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256503614-91-3
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.
  • $35
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6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
T5010570458-73-0
6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.
  • $58
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6-Chloro-7-deazapurine-β-D-riboside
T3734816754-80-6
6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.
  • $33
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Tenovin-6 Hydrochloride
T84801011301-29-3
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .
  • $33
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GLP-1(7-37) acetate(106612-94-6 free base)
TP13761450806-98-0
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
  • $113
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6-Hydroxyluteolin 7-glucoside
TN131554300-65-1
6-Hydroxyluteolin 7-glucoside is derived from Tanacetum parthenium and T. vulgare showing anti-inflammatory effects.
  • $197
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6-Hydroxykaempferol 7-O-β-glucopyranoside
T8326570056-55-2
6-Hydroxykaempferol 7-O-β-glucopyranoside (compound 5), a flavonol, has been isolated from the plant Tagetes minuta (wild marigold) [1].
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N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
T64879162012-67-1
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T64879 and the CAS number is 162012-67-1.
    7-10 days
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    L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
    TN144788700-35-0
    Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis.
    • $250
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    1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
    T66423112811-57-1
    1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66423 and the CAS number is 112811-57-1.
      7-10 days
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      Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride
      T3483696313-22-3
      Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride is a bioactive chemical.
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      5,​6,​7,​40-​Tetrahydroxyisoflavo​ne-​6,​7-​di-​o-​b-​D-​glucopyranoside
      TN12851219001-04-3
      5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-beta-D-glucopyranoside is a natural product
      • $300
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      6',7'-Dihydroxybergamottin
      TN3147264234-05-1
      6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhibit nifedipine oxidation in a concentration-dependent manner.
      • $3,006
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      11-Hydroxydrim-7-en-6-one
      TN258474635-87-3
      11-Hydroxydrim-7-en-6-one is a natural product for research related to life sciences. The catalog number is TN2584 and the CAS number is 74635-87-3.
      • $590
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      5,4'-Dihydroxy-7-methoxy-6-methylflavane
      T83307770729-34-5
      Compound 15, known as 5,4'-Dihydroxy-7-methoxy-6-methylflavane, is a natural product present in Chinese Dragon’s Blood [1].
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      Isoorientin-7-O-[6-sinapoyl]-glucoside
      TN80361016970-96-9
      Isoorientin-7-O-[6-sinapoyl]-glucoside is a phenolic compound that can be isolated from the leaves of barley.
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      7-Amino-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
      T67151172426-88-9
      7-Amino-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T67151.
        7-10 days
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        3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone
        TN10881178-24-1
        3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis.
        • $89
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        6',7'-Epoxybergamottin
        T37810206978-14-5
        6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transporter substrate, across Caco-2 cell monolayers (IC50 = 0.7 μM). 6'7'-Epoxybergamottin also has insecticidal properties with a concentration of 5 μg/cm2 leading to 100% mortality of adult olive fruit flies.
        • $115
        35 days
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        5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione
        TN3104106894-43-3
        5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione is a natural product for research related to life sciences. The catalog number is TN3104 and the CAS number is 106894-43-3.
        • $660
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        CDK4/6-IN-7
        T617382649120-20-5
        CDK4 6-IN-7, a highly potent and selective orally active inhibitor of CDK4 6, demonstrates impressive inhibition activity with IC50 values of 1.58 nM and 4.09 nM respectively. This compound is particularly valuable for breast cancer research [1].
        • $1,520
        6-8 weeks
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        6-Chloro-7-deazapurine-2F-β-D-arabinofuranose
        TNU0055169516-60-3
        6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a nucleoside, specifically a 7-deazapurine nucleoside, classified also as a fluoronucleoside and halo nucleoside; it is an arabino-nucleoside.
        • Inquiry Price
        7-10 days
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        (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
        T66550314771-88-5
        (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66550 and the CAS number is 314771-88-5.
          7-10 days
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          Theophylline, 7-ethyl-6-thio-
          T3483992985-74-5
          Theophylline, 7-ethyl-6-thio- is a bioactive chemical.
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          6',7'-Dihydroxybergamottin acetonide
          TN3146684217-08-1
          6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans.
          • $1,620
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          Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside
          TN80271016970-92-5
          Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside is a flavonoid compound identified in the leaves of barley (Hordeum vulgare L.). It exhibits antioxidant and anti-inflammatory activities.
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          (D-His(Bzl)6)-LHRH (1-7) (free acid)
          TP27551926163-27-0
          (D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide derived from luteinizing hormone-releasing hormone (LHRH). It achieves enhanced stability and biological activity through the introduction of non-natural amino acid residues at specific positions within the LHRH molecule. This modification extends the drug's half-life in the body, reduces its rate of rapid metabolism and clearance, and subsequently increases its efficacy in inhibiting cell proliferation.
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          Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside
          T832091220269-61-3
          Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside, also known as compound 8, is a flavonoid glycoside isolated from the leaf extract of the black locust (Leguminosae) [1].
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          Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)
          T83210661470-06-0
          Acacetin 7-O-(6″-O-α-L-rhamnopyranosyl-β-sophoroside), a flavonoid glycoside, has been isolated from Valeriana jatamansi Jones [1].
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          7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol
          T832532414314-11-5
          7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol, a cuminol glycoside, can be isolated from *Rhodiola rosea*^[1].
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          6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride
          T644051006-21-9
          6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64405 and the CAS number is 1006-21-9.
            7-10 days
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            2-Amino-6-(propylamino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one hydrochloride
            T64682
            2-Amino-6-(propylamino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64682.
              7-10 days
              Inquiry
              t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
              T66069147489-06-3
              t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is a useful organic compound for research related to life sciences. The catalog number is T66069 and the CAS number is 147489-06-3.
                7-10 days
                Inquiry
                Formononetin, 7-O-[?-D-Apiofuranosyl-(1?6)-?-D-glu
                T129516
                Formononetin, 7-O-[?-D-Apiofuranosyl-(1?6)-?-D-glu is a useful organic compound for research related to life sciences and the catalog number is T129516.
                • Inquiry Price
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                (4R,5R,6S)-4-Nitrobenzyl 3-((diphenoxyphosphoryl)oxy)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
                T6625390776-59-3
                (4R,5R,6S)-4-Nitrobenzyl 3-((diphenoxyphosphoryl)oxy)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66253 and the CAS number is 90776-59-3.
                  7-10 days
                  Inquiry
                  5,​7,​3'-​Trihydroxy-​6,​4',​5'-​trimethoxyflavone
                  TN128778417-26-2
                  5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone is a natural product derived from *Artemisia argyi*.
                  • $100
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                  6-Chloro-7-deaza-9-(2’,3’,5’-tri-O-acetyl-b-D-ribofuranosyl)purine
                  TNU130116754-79-3
                  Nucleoside Derivatives - 7-Deazapurine nucleosides; Halo-nucleosides; Scaffolds and Templates
                  • Inquiry Price
                  7-10 days
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                  3,11-Dihydroxy-7-drimen-6-one
                  T130890
                  3,11-Dihydroxy-7-drimen-6-one is a useful organic compound for research related to life sciences and the catalog number is T130890.
                  • Inquiry Price
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                  Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
                  T66226536759-91-8
                  Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66226 and the CAS number is 536759-91-8.
                    7-10 days
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                    (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
                    T65944355806-00-7
                    (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester is a useful organic compound for research related to life sciences. The catalog number is T65944 and the CAS number is 355806-00-7.
                      7-10 days
                      Inquiry
                      Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, methiodide
                      T3483797194-78-0
                      Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, methiodide is a bioactive chemical.
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                      2',4',5',7'-Tetrabromo-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid
                      T663483561-24-8
                      2',4',5',7'-Tetrabromo-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T66348.
                        7-10 days
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                        Kaempferol 3-O-(6''-O-acetyl)glucoside-7-O-rhamnoside
                        T124437
                        Kaempferol 3-O-(6''-O-acetyl)glucoside-7-O-rhamnoside is a useful organic compound for research related to life sciences and the catalog number is T124437.
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                        Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
                        TN62871448779-19-8
                        Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6287 and the CAS number is 1448779-19-8.
                        • $2,439
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                        2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene
                        TN28411175543-03-9
                        2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene is a natural product from the culture medium of the marine-derived fungus Aspergillus insuetus (OY-207).
                        • $860
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                        7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin
                        TN6207118584-19-3
                        7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin is a natural product for research related to life sciences. The catalog number is TN6207 and the CAS number is 118584-19-3.
                        • $740
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                        GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
                        T36380
                        GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans. Dig. Dis. Sci. 34(5), 703-708 (1989).2. Gelling, R.W., Du, X.Q., Dichmann, D.S., et al. Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice. Proc. Natl. Acad. Sci. U.S.A. 100(3), 1438-1443 (2003). GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2 References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans. Dig. Dis. Sci. 34(5), 703-708 (1989).2. Gelling, R.W., Du, X.Q., Dichmann, D.S., et al. Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice. Proc. Natl. Acad. Sci. U.S.A. 100(3), 1438-1443 (2003).
                        • $458
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                        GLP-1 (9-36) amide
                        TP2252161748-29-4
                        antagonist at the human GLP-1 receptor
                        • $81
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                        GLP-1(7-36), amide acetate
                        TP11411119517-19-9
                        GLP-1(7-36) Acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
                        • $198
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                        GLP-1(7-37) TFA salt
                        T64553
                        The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine into the bloodstream in response to food and stimulate insulin secretion. GLP-1(7-37) produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in Sprague-Dawley Rats at a dosing rang of 0.5, 5, or 50 pmol/min/kg. Further, infusion of GLP-1(7-37) for 60 mins produced a small transitory increase in plasma insulin concentration in fasted rats and fed rats and a slight transitory decrease in plasma glucose concentration. Moreover, GLP-1(7-37) (5 pmol/min/kg IV) infusion for 6 h in Sprague-Dawley rats produced a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle[1].
                          7-10 days
                          Inquiry
                          GLP-1(7-36), amide
                          T3984107444-51-9
                          GLP-1(7-36) amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient intake. It binds to the GLP-1 receptor in the pancreas, enhancing insulin secretion from pancreatic β-cells and increasing insulin expression, thereby exhibiting antidiabetic effects.
                          • $185
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                          GLP-1(7-37)
                          TP1306106612-94-6
                          GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.
                          • $1,420
                          35 days
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