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Saccharides and Glycosides

Saccharides are organic compounds composed of carbon, hydrogen, and oxygen three elements.Saccharide compounds are closely related to human life. sugar is the main source of human energy. Saccharide is also closely related with drugs. For example, the patient needs glucose injection, dextran for plasma preparations; production of tablets commonly used starch as excipients; saccharides contained in some traditional Chinese medicine has a physiological activity, such as Poria Charges carbohydrate on mice sarcoma S100 which have a strong inhibition PUPS ; lentinan also strong inhibition of tumor. A glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body.

Bleomycin Sulfate
NSC125066, Blenoxane
T61169041-93-4
Bleomycin sulfate is a glycopeptide antibiotic with antitumor activity. It is commonly used as a DNA-damaging agent and DNA synthesis inhibitor. It functions by inducing DNA strand breaks without affecting RNA strands. Bleomycin sulfate is widely used in cancer research and for establishing pulmonary fibrosis animal models.
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Quercetin
Sophoretin
T2174117-39-5
Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
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Lipopolysaccharides, Escherichiacoli
Lipopolysaccharide, E. coli O111:B4
T4107893572-42-0
Lipopolysaccharides from Escherichia coli O111:B4 are key components of the outer membrane of Gram-negative bacteria. As a smooth-type LPS, they consist of lipid A, an R3-type core oligosaccharide, and an O-specific polysaccharide. These LPS molecules exhibit high immunogenicity, can trigger strong immune responses and gastric disorders by activating the TLR-4 receptor on immune cells, and help maintain the structural integrity of the bacterial outer membrane while protecting against bile salts and lipid-based antibiotics. They are widely used to establish inflammation-related disease models, such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS).
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Heparan Sulfate
T193559050-30-0
Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG) that is tightly attached to cell surface or extracellular matrix proteins.
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Hyperoside
Quercetin 3-galactoside, Hyperin
T2844482-36-0
Hyperoside (Hyperin) is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.
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Heparin
Dalteparin, Certoparin, Bemiparin, Adomiparin
T206549005-49-6
Heparin (Adomiparin) is a mucopolysaccharide sulfate often used as an anticoagulant in clinical medicine.Heparin has shown partial anti-inflammatory activity in in vivo experiments.
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Nicotinamide riboside chloride
T622023111-00-4
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
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Cynaroside
Luteoloside, Luteolin 7-β-D-Glucopyranoside, Luteolin 7-O-β-D-glucoside, Luteolin 7-O-Glucoside, Luteolin 7-glucoside
T33765373-11-5
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
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D-Glucose
Grape sugar, Glucopyranose, Dextrose, D(+)-Glucose
T088750-99-7
D-Glucose (Glucopyranose) is a monosaccharide, a natural glucose, a sweetener. D-Glucose is the main functional substance of living organisms, and is used as a nutrient in medicine, with diuretic, detoxification and cardiotonic effects.
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MALTOTETRAOSE
α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose
T578534612-38-9
Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.
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T6A
t-6-A, t(6)A, t 6 A, N6-Threonylcarbamoyladenosine, N-(6-Nebularinylcarbamoyl)threonine
T3476524719-82-2
T6A (N6-Threonylcarbamoyladenosine) is a ubiquitously conserved nucleoside, which is essential for modification. T6A is found in the tRNA responsible for transporting the ANN codon.
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Ascamycin
T1432991432-48-3In house
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It exhibits selective antibacterial activity against Xanthomonas species, inhibiting Xanthomonas citri, Xanthomonas oryzae, and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL, and 12.5 μg/mL respectively.
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N-Acetylneuraminic acid
NeuAc, Lactaminic acid, Acide aceneuramique
T1638131-48-6
N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown that N-Acetylneuraminic acid is biologically useful for neurotransmission, leukocyte extravasation, viral or bacterial infections, and carbohydrate-protein recognition.
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Hyaluronic acid
Hyaluronate, hyaluronan
T37629004-61-9
Hyaluronic acid (hyaluronan) is a glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour, umbilical cord, synovial fluid and the capsule of certain microorganisms contributing to adhesion, elasticity, and viscosity of extracellular substances.
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Puerarin
Kakonein
T28153681-99-0
Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.
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D(+)-Raffinose pentahydrate
Raffinose pentahydrate, D-Raffinose pentahydrate
T3S030917629-30-0
D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) is a naturally occurring trisaccharide composed of fructose, galactose, and glucose, found in various vegetables and grains. It functions as a functional oligosaccharide.
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Abrusoside D
(+)-Abrusoside D
T205968125003-00-1
Abrusoside D is a triterpenoid saponin found in Abrus precatorius and can be used as a sweetener.
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1F-fructofuranosylnystose
T577259432-60-9
1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.
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Acarbose
BAY g 5421
T024756180-94-0
Acarbose (BAY g 5421) is a hypoglycemic agent that is an inhibitor of orally active alpha-glucosidase (IC50=11 nM). Acarbose enhances the hypoglycemic effect of sulfonylureas or insulin.
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Chitobiose Octaacetate
T3785041670-99-9
Chitobiose Octaacetate is a chitosan derivative formed from the acetylation of chitin, useful for synthesizing chitosan oxazoline and other chitin precursors.
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Eurycomanol 2-O-β-D-glucopyranoside
TN7028126260-97-7
Eurycomanol 2-O-β-D-glucopyranoside, a natural diterpenoid compound, is extracted from Tongkat Ali.
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D-(+)-Fucose
T2O27073615-37-0
D-(+)-Fucose is a non-metabolizable analog of l-arabinose and an inducer of β-methylgalactoside permease. It inhibits the induction of the l-arabinose manipulator and blocks the growth of Escherichia coli B/r on mineral salts medium with l-arabinose.
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D(+)-Galactosamine hydrochloride
D-Galactosamine HCl
T39991772-03-8
D(+)-Galactosamine hydrochloride is a well-established experimental toxin that induces liver injury primarily by generating free radicals and depleting UTP nucleotides, and it can be used to establish lipopolysaccharide/D-Galactosamine-induced hepatitis or acute liver injury models.
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Laminaran
β-1,3-Glucan
T157059008-22-4
Laminaran is a β-1,3-glucan isolated from brown algae, often serving as a typical ligand for Dectin-1. It possesses anti-cancer, immune-modulating, and radiation-protective properties. Laminaran can be catalyzed by glucanase. In in vitro and in vivo experiments, Laminaran has demonstrated anti-tumor activity and may be used for severe cancers.
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