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productview/AMG-337.html

" in TargetMol Product Catalog

Inhibitors & Agonists
2

AMG-337

T32091173699-31-4

AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).

c-Met/HGFR

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AMG-337 monohydrate

T703181643590-78-6

AMG-337 monohydrate is a highly selective small molecule MET inhibitor. Aberrant hepatocyte growth factor (HGF)/MET signaling has been implicated in hepatocarcinogenesis, suggesting that MET may serve as an attractive therapeutic target in hepatocellular carcinoma.

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$1,520

1-2 weeks

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