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Angiogenesis related Compound Library

Catalog No. L4800
  Library Compound List   Excel SDF

Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue. However, uncontrolled angiogenesis underlies many deadly and debilitating conditions, including cancer, skin diseases, immune disorders, diabetic ulcers, cardiovascular disease, stroke, critical limb ischemia, and many others. Therefore, angiogenesis has become an attractive target for combating diseases characterized by either poor vascularization or abnormal vasculature. For example, angiogenesis plays a critical role in the growth of cancer. Tumors induce blood vessel growth (angiogenesis) by secreting various growth factors (e.g. VEGF) and proteins which induce capillary growth into the tumor, providing it with oxygen and nutrients. Angiogenesis is also required for the spread of a tumor, or metastasis. Therefore, angiogenesis inhibitors can be used to treat cancer. In addition, proangiogenic therapies are being explored as options to treat ischemic cardiovascular diseases by formation of “natural bypasses”—that is, collateral vessels.

The TargetMol’s Angiogenesis related Compound Library, a unique collection of angiogenesis related compounds, can be used for research in angiogenesis and related drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
  • Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc.;
  • Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L4800)

Library Composition

5-HT Receptor (238)
PI3K (133)
EGFR (127)
VEGFR (116)
JAK (73)
Dopamine Receptor (69)
Src (69)
PDGFR (67)
FGFR (60)
FLT (60)
TNF (59)
Akt (55)
RAAS (52)
c-Kit (51)
COX (50)
Bcr-Abl (47)
ALK (43)
MMP (42)
mTOR (36)
Adrenergic Receptor (36)
BTK (31)
IL Receptor (29)
c-Met/HGFR (28)
AChR (26)
Tyrosine Kinases (26)
HER (25)
HIF (25)
DNA-PK (24)
TGF-beta/Smad (21)
Norepinephrine (20)
c-RET (18)
NF-κB (18)
FAK (18)
CDK (17)
Histamine Receptor (17)
ERK (17)
Syk (16)
Raf (16)
TAM Receptor (16)
STAT (14)
PKC (14)
Aurora Kinase (14)
PKA (11)
Autophagy (11)
IGF-1R (11)
p38 MAPK (10)
Potassium Channel (9)
S6 Kinase (8)
MEK (8)
Apoptosis (8)
CSF-1R (7)
AMPK (7)
Tyrosinase (7)
Trk receptor (7)
c-Fms (7)
Caspase (7)
HIF/HIF Prolyl-Hydroxylase (6)
JNK (6)
HDAC (6)
ROS (6)
Integrin (6)
ATM/ATR (6)
P450 (5)
Ephrin Receptor (5)
Antioxidant (5)
Casein Kinase (5)
PDE (5)
NOS (5)
Lipoxygenase (5)
Antifection (4)
PYK2 (4)
Carbonic Anhydrase (4)
Opioid Receptor (4)
Chk (4)
MLK (4)
DNA/RNA Synthesis (4)
Endogenous Metabolite (4)
IκB/IKK (4)
GSK-3 (4)
Estrogen/progestogen Receptor (4)
P-gp (3)
NOD (3)
Hck (3)
Survivin (3)
Sigma receptor (3)
MRP (3)
Dehydrogenase (3)
Serine Protease (3)
Microtubule Associated (3)
MAPK (3)
PARP (3)
Glucokinase (3)
Tie-2 (3)
BCL (3)
Adenosine Receptor (3)
PPAR (3)
HSP (3)
PLK (3)
PDK (3)
TRP/TRPV Channel (3)
Sodium Channel (3)
ribosome (2)
BACE (2)
Serine/threonin kinase (2)
ACK (2)
CaMK (2)
Nrf2 (2)
ROCK (2)
Histone Methyltransferase (2)
HCV Protease (2)
ATPase (2)
Prostaglandin Receptor (2)
Discoidin Domain Receptor (DDR) (2)
VDA (2)
transporter (2)
Transferase (2)
TLR (2)
MAO (2)
LDL (2)
GluR (2)
NADPH (2)
Sirtuin (1)
Antibacterial (1)
Antibiotic (1)
Calcium Channel (1)
Beta Amyloid (1)
Gap Junction Protein (1)
Reverse Transcriptase (1)
Antiviral (1)
TACC (1)
Topoisomerase (1)
Antifungal (1)
ROR (1)
ATP Citrate Lyase (1)
SGK (1)
S1P Receptor (1)
Serotonin Transporter (1)
GPR (1)
Endothelin Receptor (1)
PTEN (1)
DNA Alkylator/Crosslinker (1)
Monoamine Transporter (1)
FAAH (1)
LTR (1)
LRRK2 (1)
Hedgehog/Smoothened (1)
DNA Alkylation (1)
IRAK (1)
NADPH-oxidase (1)
DYRK (1)
Immunology & Inflammation related (1)
Epigenetic Reader Domain (1)
IFNAR (1)
HSV (1)
HIV Protease (1)
CXCR (1)
Chloride channel (1)
PKM (1)
GST (1)
GRK (1)
Pim (1)
PI4K (1)
Phospholipase (1)
PGE Synthase (1)
CCR (1)
Parasite (1)
NMDAR (1)
p97 (1)
GABA Receptor (1)
cell cycle arrest (1)
P2 Receptor (1)
CFTR (1)
HBV (1)
NO Synthase (1)
Free radical scavengers (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE