Diversity Core Library Part1

Catalog No. DF4500

Finding compounds with drug potential in the vast chemical space is a significant challenge in drug screening. Combinatorial chemistry strategies allow for the rapid construction of compound libraries containing hundreds of thousands of small molecules. These small molecules obtained in this way have similar structures and demonstrate some correlation in biological activity. Conversely, diversity-oriented synthesis (DOS) strategy involves the synthesis of small molecules with greater structural diversity. These molecules are more evenly distributed in chemical space, thus providing a better sampling of the chemical landscape. Screening these small molecules makes it possible to discover more promising drug-like structures. The Diversity Core Library Part 1 comprises over 50,000 compounds selected from a pool of 1.6 million compounds. This collection emphasizes the diversity of compound structures obtained after filtering out PAINS, REOS and MedChem filters. Therefore, it is a superior choice when looking for diverse compound structures. TargetMol's Diversity Core Library Part 1 is available in liquid form in 96-well plate packaging, with customized options also provided to meet customer needs.

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