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Reprogramming Compound Library

Catalog No. L8110
  Library Compound List   Excel SDF

Cellular reprogramming refers to the process by which differentiated somatic cells are reversed to a pluripotent or totipotent state under certain conditions. Traditional reprogramming techniques have limitations in clinical applications due to problems such as the integration of exogenous genes, while the study of small molecule compounds to induce pluripotent stem cells has opened up a new approach to somatic cell reprogramming.

Small molecule compound-induced reprogramming has a lot of advantages. For instance, integration into the genome can be avoided, so as immunogenicity; the target can be acted upon directly through the cell membrane with simple manipulation; effects are reversible, multiple targets can be regulated at the same time, and cell fates are controlled precisely.

Small molecule compound-induced pluripotent stem cells have great potential in drug discovery, cell therapy, and disease modeling, opening up new avenues for the treatment of major diseases.

TargetMol’s Reprogramming Compound Library is a unique collection of 1840 bioactive small molecule compounds of cellular reprogramming-related signaling pathways, providing an effective tool for cellular reprogramming research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
Request Library
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Product Description

  • A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
  • Targets include MEK, TGF-β, GSK3, wnt, etc.
  • Structural diversity, significant pharmaceutical efficacy, and cell permeability.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • Various assays such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the product and reduce false positives.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L8110)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

PI3K (129)
EGFR (123)
VEGFR (118)
JAK (73)
Histone Methyltransferase (71)
Epigenetic Reader Domain (67)
mTOR (65)
PDGFR (65)
HDAC (64)
ERK (58)
STAT (58)
FGFR (56)
Raf (54)
c-Met/HGFR (54)
p38 MAPK (54)
Src (53)
Wnt/beta-catenin (52)
Akt (51)
c-Kit (47)
AMPK (43)
CDK (42)
GSK-3 (40)
FLT (37)
PKC (36)
MEK (35)
JNK (32)
DNA-PK (31)
TGF-beta/Smad (30)
NF-κB (30)
DNA/RNA Synthesis (27)
Tyrosine Kinases (26)
ALK (25)
HIF (25)
MAPK (24)
Bcr-Abl (24)
HER (24)
Ras (23)
ATM/ATR (22)
ROCK (22)
S6 Kinase (22)
MAO (22)
Hedgehog/Smoothened (21)
Autophagy (20)
Apoptosis (19)
Sirtuin (19)
PKA (17)
c-RET (17)
Mitochondrial Metabolism (14)
c-Myc (14)
PDK (13)
Retinoid Receptor (13)
TAM Receptor (13)
TNF (12)
Aurora Kinase (12)
Pim (12)
PPAR (12)
Nucleoside Antimetabolite/Analog (12)
Gamma-secretase (11)
PERK (11)
HIF/HIF Prolyl-Hydroxylase (11)
Potassium Channel (11)
COX (11)
TLR (11)
Rho (10)
IGF-1R (9)
IL Receptor (9)
Casein Kinase (9)
DNA Methyltransferase (9)
c-Fms (8)
ROS (8)
MMP (8)
Caspase (8)
Chk (7)
Tyrosinase (7)
P450 (7)
Trk receptor (7)
Dehydrogenase (7)
IκB/IKK (7)
AChR (7)
CSF-1R (6)
Calcium Channel (6)
MLK (6)
Adrenergic Receptor (6)
Beta Amyloid (6)
BTK (5)
Carbonic Anhydrase (5)
Syk (5)
BCL (5)
5-HT Receptor (5)
FAK (5)
p53 (5)
Estrogen/progestogen Receptor (5)
MNK (5)
ASK (4)
Antiviral (4)
Antioxidant (4)
Antifection (4)
PTEN (4)
Glucokinase (4)
SIK (4)
HSP (4)
Histone Demethylase (4)
Endogenous Metabolite (4)
Serine Protease (4)
Ephrin Receptor (4)
DNA Alkylation (4)
Tie-2 (4)
Sodium Channel (4)
Transferase (4)
GABA Receptor (3)
NOS (3)
TOPK (3)
Antibacterial (3)
PARP (3)
PDE (3)
ATPase (3)
PLK (3)
NADPH (3)
LDL (3)
Histamine Receptor (3)
Microtubule Associated (3)
Topoisomerase (3)
Integrin (3)
Hck (3)
LRRK2 (3)
MELK (3)
Antibiotic (2)
Serine/threonin kinase (2)
GTPase (2)
PYK2 (2)
Proton pump (2)
PI4K (2)
CaMK (2)
ACK (2)
Porcupine (2)
Parasite (2)
HSV (2)
GRK (2)
S1P Receptor (2)
Reverse Transcriptase (2)
SGK (2)
BACE (2)
NADPH-oxidase (2)
ATP Citrate Lyase (2)
cholecystokinin (2)
HCV Protease (2)
Discoidin Domain Receptor (DDR) (2)
TRP/TRPV Channel (1)
RAR/RXR (1)
UGT (1)
Prostaglandin Receptor (1)
Vitamin (1)
ROR (1)
transporter (1)
SGLT (1)
RAAS (1)
ABC (1)
Phospholipase (1)
CFTR (1)
FAAH (1)
E1/E2/E3 Enzyme (1)
DUB (1)
Dopamine Receptor (1)
DNA (1)
DHFR (1)
CXCR (1)
Chloride channel (1)
Carboxypeptidase(CPG2) (1)
Gap Junction Protein (1)
Cannabinoid Receptor (1)
BMI-1 (1)
Aromatase (1)
Arginase (1)
Antifungal (1)
Antifolate (1)
Androgen Receptor (1)
AhR (1)
Fatty Acid Synthase (1)
Glucocorticoid Receptor (1)
Phosphatase (1)
Mitophagy (1)
P-gp (1)
PAI-1 (1)
PAFR (1)
p97 (1)
Nrf2 (1)
NPC1L1 (1)
NO Synthase (1)
Monoamine Oxidase (1)
Mdm2 (1)
GluR (1)
Lipoxygenase (1)
Influenza Virus (1)
IFNAR (1)
HIV Protease (1)
Histone Acetyltransferase (1)
Hippo pathway (1)
HBV (1)
GPX (1)
Hydroxylase (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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