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Stem Cell Differentiation Compound Library

Catalog No. L8000
  Library Compound List   Excel SDF

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1213 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
  • Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
  • Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L8000)

Library Composition

PI3K (133)
JAK (74)
mTOR (62)
PPAR (61)
STAT (61)
Akt (56)
Wnt/beta-catenin (52)
Histone Methyltransferase (50)
p38 MAPK (47)
GSK-3 (40)
CDK (38)
AMPK (35)
ERK (35)
TGF-beta/Smad (30)
ALK (28)
DNA-PK (28)
EGFR (27)
Tyrosine Kinases (26)
Src (25)
Gamma-secretase (24)
PKC (24)
Casein Kinase (23)
NF-κB (23)
S6 Kinase (22)
ROCK (22)
Histone Demethylase (21)
VEGFR (21)
p53 (21)
Hedgehog/Smoothened (21)
IGF-1R (21)
PKA (20)
ATM/ATR (19)
FLT (18)
MEK (17)
Autophagy (16)
Aurora Kinase (14)
DNA Methyltransferase (13)
Bcr-Abl (12)
Raf (12)
Mdm2 (12)
JNK (12)
CXCR (11)
COX (11)
Sirtuin (11)
PDGFR (11)
Apoptosis (10)
FGFR (9)
Potassium Channel (9)
HDAC (9)
PDK (9)
PDE (9)
c-Kit (9)
Endogenous Metabolite (9)
DNA/RNA Synthesis (8)
P450 (8)
ATPase (8)
BACE (8)
Beta Amyloid (8)
Epigenetic Reader Domain (8)
TNF (8)
IL Receptor (8)
Adrenergic Receptor (8)
Histone Acetyltransferase (8)
Caspase (7)
Retinoid Receptor (6)
5-HT Receptor (6)
Carbonic Anhydrase (6)
c-RET (6)
AChR (6)
c-Met/HGFR (6)
MMP (5)
ROS (5)
MAPK (5)
Porcupine (5)
Estrogen/progestogen Receptor (5)
Chk (5)
Dehydrogenase (5)
Sodium Channel (5)
IκB/IKK (4)
Pim (4)
OCT (4)
BTK (4)
PARP (4)
Glucokinase (4)
Rho (4)
MAO (3)
c-Fms (3)
LRRK2 (3)
c-Myc (3)
BCL (3)
Mitochondrial Metabolism (3)
MLK (3)
Syk (3)
Lipoxygenase (3)
Serine Protease (3)
Vitamin (3)
Smo (3)
GABA Receptor (3)
Antioxidant (3)
Histamine Receptor (3)
Hippo pathway (3)
PTEN (3)
Antibiotic (3)
HER (3)
FAK (3)
Trk receptor (2)
NADPH-oxidase (2)
AhR (2)
PI4K (2)
Parasite (2)
Tyrosinase (2)
transporter (2)
Antiviral (2)
PYK2 (2)
Nrf2 (2)
NADPH (2)
Glucocorticoid Receptor (2)
MNK (2)
DYRK (2)
GRK (2)
Fatty Acid Synthase (2)
SIK (2)
SGK (2)
HCV Protease (2)
HIF (2)
Serine/threonin kinase (2)
Dopamine Receptor (2)
Calcium Channel (2)
PLK (2)
HSP (2)
S1P Receptor (2)
ABC (2)
ACK (2)
cholecystokinin (2)
Phosphatase (2)
Microtubule Associated (2)
Prostaglandin Receptor (1)
TLR (1)
Proteasome (1)
VDA (1)
UGT (1)
Topoisomerase (1)
Tie-2 (1)
TAM Receptor (1)
TACC (1)
Stemness kinase (1)
MRP (1)
HIV Protease (1)
Phosphorylase (1)
Beta-Secretase (1)
DHFR (1)
Cysteine Protease (1)
CSF-1R (1)
Chloride channel (1)
cell cycle arrest (1)
cAMP (1)
BMI-1 (1)
Aromatase (1)
DNA Alkylation (1)
Arginase (1)
Antifungal (1)
Antifection (1)
Antibacterial (1)
Amino Acids and Derivatives (1)
advanced glycation end products (1)
Adenosine Receptor (1)
DNA (1)
DNA Alkylator/Crosslinker (1)
Phospholipase (1)
Immunology & Inflammation related (1)
P-gp (1)
PAI-1 (1)
NOS (1)
NMDAR (1)
NAMPT (1)
MELK (1)
Integrin (1)
IFNAR (1)
DUB (1)
Hydroxylase (1)
HSV (1)
Histone Acetylation (1)
Hck (1)
HBV (1)
GPR (1)
GluR (1)
E1/E2/E3 Enzyme (1)
YAP (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE