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Tetrahydrocannabivarin

Catalog No. TN5131   CAS 31262-37-0
Synonyms: THCV, delta9-Tetrahydrocannabivarin, CRM, Tetrahydrocannavarin

Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in obesity, perhaps with a lowered risk of depressive side effects. Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity.

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Tetrahydrocannabivarin Chemical Structure
Tetrahydrocannabivarin, CAS 31262-37-0
Pack Size Availability Price/USD Quantity
1 mg In stock $ 1,170.00
5 mg In stock $ 2,350.00
10 mg In stock $ 3,170.00
25 mg In stock $ 4,690.00
50 mg In stock $ 6,350.00
100 mg In stock $ 8,580.00
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Purity: 96.30%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in obesity, perhaps with a lowered risk of depressive side effects. Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity.
In vitro At 3-1000 nanomol (nM), THCV did not prevent electrically induced contractions of mouse isolated vas deferens; though, the amount of THCV in this range formed dextral shifts in the log concentration-response curves of WIN and anandamide for electrically evoked contractions. These changes were not convoyed by a reduction in the maximal effect of any agonist. Nevertheless, at 3 millimolar (mM), THCV did lessen the contractile reaction of the vas deferens in a CB1 receptor antagonist (SR141716)-independent way. Moreover, THCV looks like SR141716 antagonist, which at high quantities also cooperates with non-CB1 targets.[1].
Source
Synonyms THCV, delta9-Tetrahydrocannabivarin, CRM, Tetrahydrocannavarin
Molecular Weight 286.41
Formula C19H26O2
CAS No. 31262-37-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Slightly soluble

TargetMolReferences and Literature

1. Molecular analysis of genetic fidelity in Cannabis sativa L. plants grown from synthetic (encapsulated) seeds following in vitro storage. Biotechnology Letters, 2011, 33(12):2503-2508. 2. Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity. Proceedings of the British Pharmacological Society, 2006.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Bioactive Compounds Library Max Antidepressant Compound Library Selected Plant-Sourced Compound Library ReFRAME Related Library Natural Product Library for HTS Natural Product Library Inhibitor Library Anti-Obesity Compound Library

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Keywords

Tetrahydrocannabivarin 31262-37-0 GPCR/G Protein Cannabinoid Receptor THCV O-4394 inhibit THC-V Inhibitor O4394 delta9-Tetrahydrocannabivarin CRM O 4394 Tetrahydrocannavarin inhibitor

 

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