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Anti-COVID-19 Traditional Chinese Medicine Compound Library

Catalog No. L6720
  Library Compound List   Excel SDF

During the treatment of Covid-19 in China, the intervention of traditional Chinese medicine (TCM) reduced the severe symptoms of patients and played significant role in the war against COVID-19. Multiple research studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. TCM could suppress endotoxin-induced cytotoxicity, kill the virus, reduce the virus' access to the cell and lower the incidence of a cytokine storm. To further support the research in modes of action of TCM in the treatment of COVID-19, we extracted 1162 bioactive components (monomers) from TCM prescriptions having therapeutic effect.

This library collects monomers of diverse structures, such as Flavonoids, alkaloids, Polyphenols, Terpenes, ets., from TCM prescriptions of significant therapeutic effect on COVID-19 including Lonicera japonica Thunb., Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc.

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Product Description

  • A unique collection of 1162 monomers from 70 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening;
  • Sources are 70 TCM plants including Lonicera japonica Thunb., Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc.;
  • Structurally diverse: including Flavonoids, alkaloids, Polyphenols, Terpenes, ets.;
  • NMR and HPLC validated to ensure high purity and quality.

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L6720)

Library Composition

Endogenous Metabolite (57)
NF-κB (50)
Antioxidant (48)
COX (30)
P450 (28)
Antibacterial (27)
Antifection (26)
AChR (21)
IL Receptor (20)
Apoptosis (18)
TNF (17)
Autophagy (16)
Vitamin (14)
GABA Receptor (14)
MMP (13)
ROS (12)
Tyrosinase (12)
Estrogen/progestogen Receptor (12)
ERK (12)
Calcium Channel (11)
Caspase (11)
STAT (11)
5-HT Receptor (10)
Antiviral (9)
HIV Protease (9)
Akt (9)
BCL (8)
Antifungal (8)
PPAR (8)
NOS (8)
Dehydrogenase (8)
TRP/TRPV Channel (8)
p38 MAPK (8)
Glucokinase (7)
EGFR (7)
DNA/RNA Synthesis (7)
Reductase (6)
PARP (6)
NO Synthase (6)
Adrenergic Receptor (6)
AMPK (6)
JNK (6)
PI3K (5)
PKC (5)
Antibiotic (5)
Prostaglandin Receptor (5)
Immunology & Inflammation related (5)
RAAS (5)
Beta Amyloid (5)
MAO (5)
Lipoxygenase (5)
Phosphatase (4)
mTOR (4)
CDK (4)
BACE (4)
p53 (4)
TGF-beta/Smad (4)
NOD (3)
GSK-3 (3)
Dopamine Receptor (3)
Lipid (3)
Nrf2 (3)
Sirtuin (3)
Opioid Receptor (3)
CXCR (3)
MEK (3)
ATPase (3)
IκB/IKK (3)
JAK (3)
Amino Acids and Derivatives (3)
PAFR (2)
Parasite (2)
Aromatase (2)
PDE (2)
S6 Kinase (2)
AhR (2)
PDGFR (2)
Phospholipase (2)
UGT (2)
Topoisomerase (2)
Cannabinoid Receptor (2)
Src (2)
ROR (2)
VEGFR (2)
cell cycle arrest (2)
Nucleoside Antimetabolite/Analog (2)
FAK (2)
HMG-CoA Reductase (2)
HSV (2)
HIF (2)
HDAC (2)
HCV Protease (2)
IGF-1R (2)
GST (2)
Free radical scavengers (2)
MAPK (2)
FGFR (2)
Epigenetic Reader Domain (2)
MRP (2)
NADPH (2)
Histamine Receptor (2)
DPP-4 (1)
Factor Xa (1)
Decarboxylase (1)
Wnt/beta-catenin (1)
CCR (1)
Xanthine Oxidase (1)
FAAH (1)
AChE (1)
HER (1)
DNA Alkylation (1)
advanced glycation end products (1)
Casein Kinase (1)
DNA gyrase (1)
HBV (1)
ALK (1)
Aminopeptidase (1)
Fas/FasL (1)
GPR (1)
Bcr-Abl (1)
Glutathione reductase (1)
GluR (1)
Glucocorticoid Receptor (1)
Gamma-secretase (1)
cAMP (1)
HIF/HIF Prolyl-Hydroxylase (1)
Ferroptosis (1)
Apoptosis inducer (1)
CaMK (1)
Arginase (1)
Fatty Acid Synthase (1)
ATM/ATR (1)
Androgen Receptor (1)
Tyrosine Kinases (1)
Virus Protease (1)
Monocarboxylate transporter (1)
Raf (1)
Melatonin Receptor (1)
PTEN (1)
Mitochondrial Metabolism (1)
Mitophagy (1)
Potassium Channel (1)
PKM (1)
PKA (1)
Reverse Transcriptase (1)
Pim (1)
MPO (1)
Phosphorylase (1)
MT Receptor (1)
P-gp (1)
PGE Synthase (1)
Norepinephrine (1)
c-Myc (1)
Retinoid Receptor (1)
Liver X Receptor (1)
NPC1L1 (1)
Telomerase (1)
IAP (1)
Trk receptor (1)
Transferase (1)
Transaminase (1)
IDO (1)
IFNAR (1)
TLR (1)
Syk (1)
Lipase (1)
stilbene oxidase (1)
iGluR (1)
Influenza Virus (1)
IRAK (1)
Sigma receptor (1)
Serine/threonin kinase (1)
SARS-CoV (1)
LDL (1)
Chloride channel (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE