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Autophagy Compound Library

Catalog No. L3200
  Library Compound List   Excel SDF

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1248 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 1067 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L3200)

Library Composition

Autophagy (125)
PI3K (93)
mTOR (61)
AMPK (39)
HDAC (39)
p38 MAPK (31)
CXCR (30)
Raf (28)
Akt (27)
NF-κB (26)
VEGFR (25)
DNA/RNA Synthesis (23)
p53 (23)
EGFR (23)
Aurora Kinase (22)
DNA-PK (22)
c-Kit (21)
Calcium Channel (21)
Adrenergic Receptor (21)
COX (21)
MEK (21)
ERK (20)
Bcr-Abl (20)
CDK (20)
Retinoid Receptor (19)
FLT (19)
AChR (18)
LRRK2 (18)
Apoptosis (18)
PDGFR (18)
GSK-3 (16)
Src (16)
5-HT Receptor (15)
PKC (15)
Potassium Channel (15)
Estrogen/progestogen Receptor (14)
Mdm2 (13)
Dopamine Receptor (13)
CFTR (13)
P450 (13)
Topoisomerase (13)
HMG-CoA Reductase (13)
TNF (13)
Antibacterial (12)
Sirtuin (12)
Antibiotic (12)
PKA (12)
JAK (11)
CaMK (11)
STAT (11)
FXR (11)
Sodium Channel (11)
BCL (11)
Microtubule Associated (11)
JNK (11)
PPAR (10)
Proteasome (10)
S6 Kinase (10)
c-RET (10)
FAAH (10)
FGFR (10)
ATM/ATR (10)
MMP (9)
Epigenetic Reader Domain (9)
HIF (9)
Glucocorticoid Receptor (8)
Casein Kinase (8)
PDE (8)
PERK (8)
ATPase (8)
DUB (8)
Histone Methyltransferase (7)
Tyrosine Kinases (7)
Antioxidant (7)
HIV Protease (7)
c-Met/HGFR (7)
HSP (7)
IL Receptor (7)
NADPH (7)
Histamine Receptor (6)
TLR (6)
MAO (6)
Trk receptor (6)
c-Myc (6)
Serine/threonin kinase (6)
ALK (6)
Dehydrogenase (6)
IκB/IKK (6)
Caspase (6)
Parasite (6)
GABA Receptor (6)
ROS (5)
PARP (5)
HER (5)
Rho (5)
PDK (5)
TGF-beta/Smad (5)
Glucokinase (5)
DNA Alkylation (5)
Cysteine Protease (5)
Integrin (4)
IGF-1R (4)
DNA Methyltransferase (4)
Mitophagy (4)
DHFR (4)
Lipoxygenase (4)
Serine Protease (4)
ROCK (4)
Carbonic Anhydrase (4)
Androgen Receptor (4)
ribosome (4)
Phosphatase (4)
Phospholipase (4)
PTEN (4)
MRP (4)
HCV Protease (3)
Prostaglandin Receptor (3)
Hedgehog/Smoothened (3)
IAP (3)
LDL (3)
NOS (3)
Pim (3)
RAAS (3)
transporter (3)
HIF/HIF Prolyl-Hydroxylase (3)
TRP/TRPV Channel (3)
ABC (3)
c-Fms (3)
Fatty Acid Synthase (3)
FAK (3)
Vitamin (3)
DPP-4 (3)
Amino Acids and Derivatives (3)
Endogenous Metabolite (3)
OXPHOS (2)
MAPK (2)
CCR (2)
LTR (2)
TAM Receptor (2)
p97 (2)
Cell wall (2)
Opioid Receptor (2)
SIK (2)
lysosomal autophagy (2)
Nrf2 (2)
SGK (2)
Norepinephrine (2)
Adenosine Receptor (2)
MLK (2)
AhR (2)
MNK (2)
NOD (2)
Chk (2)
VDA (2)
IDO (2)
HSV (2)
Proton pump (2)
Antiviral (2)
Gamma-secretase (2)
PLK (2)
GluR (2)
Ras (2)
GPR (2)
BACE (2)
Tyrosinase (2)
GTPase (2)
Antifection (2)
Beta Amyloid (2)
NMDAR (2)
BMI-1 (2)
BTK (2)
Dynamin (2)
Cannabinoid Receptor (2)
E1/E2/E3 Enzyme (2)
S1P Receptor (1)
Aminopeptidase (1)
Arginase (1)
PAI-1 (1)
PAFR (1)
RAR/RXR (1)
ROR (1)
CAT (1)
Reverse Transcriptase (1)
NPC1L1 (1)
Annexin A (1)
Reductase (1)
P2 Receptor (1)
Nucleoside Antimetabolite/Analog (1)
P-gp (1)
Ferroptosis (1)
SARS-CoV (1)
Hck (1)
Aromatase (1)
Thrombin (1)
Hexokinase (1)
Ephrin Receptor (1)
Tie-2 (1)
UGT (1)
HBV (1)
Histone Demethylase (1)
GRK (1)
GPCR19 (1)
TOPK (1)
Gap Junction Protein (1)
Transferase (1)
FOXO1 (1)
Vasopressin Receptor (1)
Virus Protease (1)
Na+/Ca2+ Exchanger (1)
CSF-1R (1)
MPO (1)
Mitochondrial Metabolism (1)
Melatonin Receptor (1)
Sigma receptor (1)
ACK (1)
Somatostatin (1)
Lipid (1)
iGluR (1)
Lipase (1)
Kinesin (1)
Survivin (1)
DNA (1)
IRAK (1)
DNA gyrase (1)
ATP Citrate Lyase (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE