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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1470 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
AMPK
GSK-3
Endogenous Metabolite
Antibiotic
Mitophagy
CDK
p38 MAPK
CXCR
NF-κB
HDAC
HIV Protease
DNA-PK
ERK
Ferroptosis
Parasite
Reactive Oxygen Species
Raf
S6 Kinase
VEGFR
Potassium Channel
ATM/ATR
MEK
DNA/RNA Synthesis
PDK
Src
PKC
Adrenergic Receptor
COX
Retinoid Receptor
P450
Bcr-Abl
PDGFR
EGFR
LRRK2
PKA
Calcium Channel
FLT
c-Kit
JNK
JAK
Virus Protease
PPAR
Topoisomerase
Aurora Kinase
Influenza Virus
Caspase
AChR
CFTR
Antifungal
STAT
PI4K
5-HT Receptor
TNF
Estrogen/progestogen Receptor
SARS-CoV
FGFR
HMG-CoA Reductase
Dehydrogenase
Wnt/beta-catenin
FXR
FAAH
CaMK
Casein Kinase
Ras
PDE
BCL
MMP
Nrf2
Microtubule Associated
HSV
Dopamine Receptor
ADC Cytotoxin
PERK
ROCK
IL Receptor
TLR
Proteasome
Mitochondrial Metabolism
IGF-1R
TGF-beta/Smad
MAPK
HIF/HIF Prolyl-Hydroxylase
p53
Estrogen Receptor/ERR
Nucleoside Antimetabolite/Analog
TRP/TRPV Channel
Glucocorticoid Receptor
Chk
Lipoxygenase
c-RET
Sodium Channel
ATPase
Proton pump
Antioxidant
PARP
Rho
SIK
PTEN
Epigenetic Reader Domain
HSP
Sirtuin
ALK
IκB/IKK
GABA Receptor
HIF
c-Met/HGFR
NADPH
Histamine Receptor
Phosphatase
c-Myc
P-gp
Trk receptor
MELK
Beta Amyloid
Histone Methyltransferase
HCV Protease
Integrin
Adenosine Receptor
DYRK
MRP
Tyrosine Kinases
Serine/threonin kinase
Glucokinase
Antifection
ROS
Opioid Receptor
DUB
Prostaglandin Receptor
transporter
Phospholipase
SGK
FAK
NOS
Carbonic Anhydrase
DHFR
DNA Alkylator/Crosslinker
RAAS
Progesterone Receptor
Pim
Serotonin Transporter
Cysteine Protease
MAO
RIP kinase
LDL
Gamma-secretase
Hedgehog/Smoothened
CCR
GluR
Androgen Receptor
Interleukin
Reverse Transcriptase
c-Fms
ribosome
Cannabinoid Receptor
DNA Methyltransferase
ROS Kinase
NO Synthase
Transferase
Dynamin
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Glutathione Peroxidase
GTPase
ABC
HBV
Antifolate
Aryl Hydrocarbon Receptor
P2X Receptor
DPP-4
Fatty Acid Synthase
DNA
Antiviral
CRISPR/Cas9
PLK
Syk
NOD
Tyrosinase
HER
S1P Receptor
Mdm2
NPC1L1
ROR
YAP
BACE
RAR/RXR 
Cell wall
Tie-2
iGluR
IAP
IRE1
E1/E2/E3 Enzyme
Drug Metabolite
NMDAR
Glucosidase
BTK
Monoamine Transporter
DNA Alkylation
PGC-1α
Norepinephrine
Beta-Secretase
AChE
MNK
Histone Acetyltransferase
GPR
ATTECs
BMI-1
lysosomal autophagy
AhR
NOD-like Receptor (NLR)
MLK
Kinesin
Monoamine Oxidase
Apelin receptor
Chloride channel
Adenylyl cyclase
CAT
MyD88
Arginase
LPL Receptor
Arrestin
Na+/Ca2+ Exchanger
Reductase
Lipase
gp120/CD4
TOPK
VDA
Melatonin Receptor
Serine Protease
NAMPT
PYK2
Glutaminase
FOXO1
IDO
Immunology/Inflammation related
CSF-1R
Myosin
Annexin A
UGT
PAFR
GRK
DNA gyrase
Hexokinase
Molecular Glues
Guanylate cyclase
Smo
Vasopressin Receptor
Endothelin Receptor
Somatostatin
ACK
cAMP
Indoleamine 2,3-Dioxygenase (IDO)
ATP Citrate Lyase
Lipid
BCRP
OXPHOS
Survivin
Acyltransferase
Aminopeptidase
GPCR19
Ephrin Receptor
Decarboxylase
GluCls
Ligand for E3 Ligase
Aromatase
Complement System
DAPK
Gap Junction Protein
Anti-infection
IRAK
cholecystokinin
Sigma receptor
Thrombin
p97
Imidazoline Receptor
PD-1/PD-L1